Protein

Protein accession
M1ID49 [UniProt]
Representative
3IYDg
Source
UniProt (cluster: phalp2_10774)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MARLETKYIVIHCSQTRPSQKIGAKDIDRWHRERGWLKIGYAKVIKRDGTVEQGRADDELQAHVKEYNHVSTSVCVVGGAVEENWKEPEDNFTGEQWESLKKVLEELVIKFPEARIVGHYELDERKTCPNFNVREYLLNEDIKGYKFADSTVTDGDIQEMKDAGEL
Physico‐chemical
properties
protein length:166 AA
molecular weight:19184,3 Da
isoelectric point:5,33
hydropathy:-0,76
Representative Protein Details
Accession
3IYDg
Protein name
3IYDg
Sequence length
133 AA
Molecular weight
N/A Da
Isoelectric point
4,42590
Sequence
MRNGLTEFIEKXXXXGEVQQGRADDAVQAHVRGYNHTSYGLCLVGGALEEDWTKPDNNFTAEQYESLYKVLGELVLKYPEARIVGHYELDEKKTCPNMNVREYLLNEDIPNYKFQDGLTDEADLAELEDDHEQ
Other Proteins in cluster: phalp2_10774
Total (incl. this protein): 14 Avg length: 161,0 Avg pI: 4,88
Protein ID Length (AA) pI
3IYDg 133 4,42590
1yYts 172 4,85419
4R9Sk 167 5,00231
8363j 172 4,95826
8A9FW 167 4,96457
8CwLf 166 5,33095
8zx3c 167 4,96798
Dhwc 96 4,19025
A0A4Y1NU36 166 4,90835
A0A7S5Y9C4 173 4,72937
A0A7S5YA06 173 4,72937
A0A8S0I6Y9 164 4,83662
A0AAX4G2N4 172 5,07603
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3887
6RreM
 7260 45,7% 94 4.010E-26
2 phalp2_25112
1plEg
 298 47,1% 89 3.757E-22
3 phalp2_11894
2jrH4
 329 46,8% 94 2.489E-21
4 phalp2_24952
kjdf
 441 40,7% 103 1.004E-15
5 phalp2_1572
7VT79
 79 36,9% 92 5.964E-14
6 phalp2_7367
4xnnO
 5 33,0% 100 1.529E-13
7 phalp2_25435
2NLUL
 9 38,5% 83 7.344E-13
8 phalp2_11611
1k5JO
 2203 32,2% 96 2.823E-10
9 phalp2_7876
8Bm2S
 19 33,5% 128 1.198E-08
10 phalp2_12432
kMJA
 24 33,3% 90 1.976E-07

Domains

Domains [InterPro]
Disordered region
Unannotated
Representative sequence (used for alignment): 3IYDg (133 AA)
Member sequence: M1ID49 (166 AA)
1 133 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pelagibacter phage HTVC011P
[NCBI] 		1283078 Autographiviridae > Stopavirus > Stopavirus HTVC011P
Host Candidatus Pelagibacter ubique HTCC1062
[NCBI] 		335992 Proteobacteria > Alphaproteobacteria > Pelagibacterales > Pelagibacteraceae > Candidatus Pelagibacter >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC465900 [NCBI]
CDS location
range 9643 -> 10143
strand +
CDS
ATGGCAAGACTAGAAACTAAATACATTGTGATACATTGTTCACAAACTAGACCTTCACAAAAGATAGGTGCTAAAGATATAGATAGATGGCACAGAGAAAGAGGTTGGTTAAAAATAGGTTATGCCAAAGTTATTAAAAGAGATGGTACTGTTGAGCAAGGCAGGGCAGATGATGAACTACAAGCACATGTTAAAGAATATAATCATGTATCAACTTCAGTTTGTGTAGTTGGTGGTGCAGTAGAAGAAAACTGGAAAGAACCAGAAGATAATTTTACAGGAGAACAATGGGAAAGTTTAAAGAAAGTTTTAGAAGAACTAGTAATTAAATTTCCTGAAGCAAGAATTGTAGGACATTATGAACTTGATGAAAGAAAAACATGTCCTAACTTTAATGTCAGAGAATATTTATTAAACGAAGATATTAAAGGTTACAAATTCGCAGACAGCACAGTCACTGATGGCGACATACAGGAAATGAAAGATGCAGGAGAACTCTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0002b2a3b8_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3IYDg) rather than this protein.
PDB ID
3IYDg
Method AlphaFoldv2
Resolution 59.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50