Protein

Protein accession
A0A1L6BZH5 [UniProt]
Representative
8IAfz
Source
UniProt (cluster: phalp2_2841)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MAFDYYKLEPHRYDLVPSNRYQVGRSGKKPRYIVRHHLMMVNATGEAVRGVWLDRVASAHYTVQGAAGRLGQISQHVYDSNTAYANADWNANLESYTIEHSNNSGRFNGSDYHDKAWNIADEVIIAGARWAAALLVHDKMGAPVYGPTGTIRDHNMFTPTGCPVHLSGPHGKNPFGGKAGKYHYPWMEEAKSFYNDLSKKLVNPDGTPIKHGFTPPKEESKEVSFTDADRKMLREVHHELTHRFDSRYDLERLRRGEITERQVFKESQVGYALEADRKIEDVHANMLPAIYDELTEIKAKLEKEGK
Physico‐chemical
properties
protein length:306 AA
molecular weight:34799,6 Da
isoelectric point:7,32
hydropathy:-0,75
Representative Protein Details
Accession
8IAfz
Protein name
8IAfz
Sequence length
306 AA
Molecular weight
34799,59600 Da
Isoelectric point
7,32270
Sequence
MAFDYYKLEPHRYDLVPSNRYQVGRSGKKPRYIVRHHLMMVNATGEAVRGVWLDRVASAHYTVQGAAGRLGQISQHVYDSNTAYANADWNANLESYTIEHSNNSGRFNGSDYHDKAWNIADEVIIAGARWAAALLVHDKMGAPVYGPTGTIRDHNMFTPTGCPVHLSGPHGKNPFGGKAGKYHYPWMEEAKSFYNDLSKKLVNPDGTPIKHGFTPPKEESKEVSFTDADRKMLREVHHELTHRFDSRYDLERLRRGEITERQVFKESQVGYALEADRKIEDVHANMLPAIYDELTEIKAKLEKEGK
Other Proteins in cluster: phalp2_2841
Total (incl. this protein): 3 Avg length: 297,3 Avg pI: 7,02
Protein ID Length (AA) pI
8IAfz 306 7,32270
8tgbR 280 6,40941
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_6225
6oM64
 106 35,0% 208 1.199E-30
2 phalp2_27792
7ui6P
 19 31,3% 252 5.223E-26

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 8IAfz (306 AA)
Member sequence: A0A1L6BZH5 (306 AA)
1 306 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pasteurella phage PMP-GADVASU-IND
[NCBI] 		1927015 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY203335 [NCBI]
CDS location
range 38265 -> 39185
strand +
CDS
ATGGCATTCGACTACTACAAGCTTGAACCGCACCGATATGACCTGGTGCCCAGTAATCGATACCAGGTAGGGCGCTCGGGAAAGAAACCGCGCTACATCGTGCGCCACCATTTGATGATGGTGAATGCGACTGGTGAAGCGGTGCGCGGCGTGTGGCTAGACCGAGTCGCATCAGCGCACTACACGGTGCAGGGTGCGGCGGGGAGGCTTGGCCAAATCAGCCAGCATGTTTATGACTCGAATACCGCGTATGCGAATGCCGATTGGAATGCGAATCTTGAGTCCTACACGATTGAGCATTCCAATAATTCCGGACGCTTCAATGGCAGTGATTATCACGATAAGGCGTGGAATATTGCCGATGAGGTGATTATCGCGGGTGCTCGTTGGGCGGCAGCGTTGCTGGTGCACGACAAGATGGGTGCGCCTGTATACGGCCCCACTGGCACGATTCGCGATCACAACATGTTTACTCCCACCGGTTGCCCTGTGCACCTATCCGGCCCACACGGTAAAAATCCGTTCGGCGGCAAAGCCGGTAAATACCACTACCCGTGGATGGAAGAAGCGAAAAGCTTCTACAACGACTTATCCAAGAAACTCGTAAACCCAGATGGAACCCCCATCAAGCACGGATTCACACCACCAAAAGAGGAGAGTAAAGAAGTGTCTTTTACTGACGCTGACCGTAAGATGCTGCGCGAAGTGCATCATGAGCTGACCCACCGCTTTGATTCCCGTTATGACCTTGAGCGTCTACGCCGCGGGGAAATTACCGAGCGTCAGGTGTTTAAGGAAAGCCAGGTCGGATACGCGCTGGAAGCTGACCGCAAGATTGAGGACGTCCACGCGAATATGTTGCCGGCTATCTATGACGAGCTGACCGAGATTAAAGCGAAGCTAGAAAAGGAAGGTAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8IAfz) rather than this protein.
PDB ID
8IAfz
Method AlphaFoldv2
Resolution 90.36
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50