Protein

Protein accession
A0A173G9C4 [UniProt]
Representative
7Q7F4
Source
UniProt (cluster: phalp2_39451)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MDRGIDVSAYQAPDGGLLEGMSFCIIKATEGTGYTNPNRAQWYKVATDRGVTTGAYHFMRGGDPVQQADYFLDNLPGDVGWLALDVEADDDGLEWSGRVGFILAWTDRVKTASAKPTLVYCSRSWANALWEAATSDQRTRLTALPLWLADYTGTPGTYSGPVPDGWPVTMHQFTSTPIDTNALFADILQGGDTMTPELAARLDQIVAWQDANFKALAAQADANRDTLAQWTVDRLKETAASIPNVDTDKIAAQLAGAKLVVQLPANAQLQPAPAGGQA
Physico‐chemical
properties
protein length:278 AA
molecular weight:29894,0 Da
isoelectric point:4,45
hydropathy:-0,23
Representative Protein Details
Accession
7Q7F4
Protein name
7Q7F4
Sequence length
278 AA
Molecular weight
29894,02190 Da
Isoelectric point
4,44728
Sequence
MDRGIDVSAYQAPDGGLLEGMSFCIIKATEGTGYTNPNRAQWYKVATDRGVTTGAYHFMRGGDPVQQADYFLDNLPGDVGWLALDVEADDDGLEWSGRVGFILAWTDRVKTASAKPTLVYCSRSWANALWEAATSDQRTRLTALPLWLADYTGTPGTYSGPVPDGWPVTMHQFTSTPIDTNALFADILQGGDTMTPELAARLDQIVAWQDANFKALAAQADANRDTLAQWTVDRLKETAASIPNVDTDKIAAQLAGAKLVVQLPANAQLQPAPAGGQA
Other Proteins in cluster: phalp2_39451
Total (incl. this protein): 6 Avg length: 291,3 Avg pI: 4,57
Protein ID Length (AA) pI
7Q7F4 278 4,44728
7AcPG 298 4,62410
7Aem3 298 4,62660
A0A1D8ETQ2 298 4,62410
A0A1D8EU28 298 4,62660
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27394
4HDMm
 9 33,8% 204 5.857E-20
2 phalp2_34559
4UNXW
 287 37,7% 180 1.072E-19
3 phalp2_20117
23DDy
 70 34,8% 192 2.193E-18
4 phalp2_33827
1mUYf
 73 35,3% 198 5.412E-18
5 phalp2_2609
6KgoW
 1 31,7% 290 5.987E-17
6 phalp2_5615
4g2xP
 40 34,9% 183 8.081E-17
7 phalp2_37341
8v6XY
 562 32,7% 183 1.985E-16
8 phalp2_38994
84ePK
 348 32,9% 182 3.613E-16
9 phalp2_30706
7cHI2
 66 32,4% 188 3.613E-16
10 phalp2_39912
1jXPT
 300 32,7% 183 6.570E-16

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 7Q7F4 (278 AA)
Member sequence: A0A173G9C4 (278 AA)
1 278 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Propionibacterium phage PFR1
[NCBI] 		1838137 Pulverervirus > Pulverervirus PFR1
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KU984979 [NCBI]
CDS location
range 17734 -> 18570
strand +
CDS
ATGGATCGTGGCATTGACGTGTCCGCCTATCAGGCCCCCGATGGTGGCCTGCTGGAGGGCATGTCGTTTTGCATCATCAAGGCCACCGAAGGCACCGGCTATACGAACCCGAATCGTGCCCAGTGGTACAAGGTCGCCACGGATCGTGGGGTAACCACAGGCGCCTACCACTTCATGCGTGGCGGCGACCCAGTCCAGCAGGCCGACTACTTCCTGGACAACCTCCCCGGTGACGTCGGGTGGTTGGCGCTAGACGTGGAAGCCGACGACGACGGCTTGGAGTGGTCCGGGCGGGTCGGTTTCATCCTCGCCTGGACTGACCGGGTGAAGACTGCCAGCGCTAAACCCACGCTGGTCTATTGCTCGCGGTCGTGGGCGAACGCCCTGTGGGAGGCCGCCACCAGCGACCAGCGCACACGCTTGACCGCTCTCCCGCTGTGGCTGGCCGACTACACCGGAACCCCCGGCACCTACTCGGGGCCGGTCCCCGATGGGTGGCCGGTGACCATGCACCAATTCACTTCGACCCCGATCGACACCAATGCACTATTCGCTGACATTCTCCAAGGAGGAGACACCATGACACCCGAACTAGCCGCGCGCCTCGATCAGATCGTGGCATGGCAGGACGCCAACTTCAAAGCGCTCGCCGCCCAAGCCGACGCGAACCGGGACACCTTGGCACAGTGGACCGTGGACCGGCTGAAAGAGACCGCCGCTTCGATCCCCAACGTCGACACCGACAAGATCGCCGCCCAACTCGCGGGCGCGAAACTGGTCGTCCAACTGCCCGCCAACGCACAACTCCAGCCCGCTCCCGCAGGGGGTCAGGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi0005a5ccff_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7Q7F4) rather than this protein.
PDB ID
7Q7F4
Method AlphaFoldv2
Resolution 77.84
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50