Protein

Protein accession
Q9MBI0 [UniProt]
Representative
7PxDe
Source
UniProt (cluster: phalp2_17457)
Protein name
Gp24, lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVPKVRDWTARFLFGGPRSTSKLIGVCIHTTENDPSTPAENVANYQINSQSGSYHTLADRQGILRENTADWITWSTGNQGNTLLMHLSFVARASMTRAQWLAEDAMLRNGAWEVAQWCKKFGWPVRHVDVAGLPGITTHNATRVWGSTDHTDPGPNFPWDVFLSYVNQEVNGGATPAPTPTPEEDNTVMALLTGVSATALDIVRRGVTTLVTPLQSIINPKKSYLITDLVRFIDATAWENRVYLRELLREQGKNPDTIRDEAIKRDRGEA
Physico‐chemical
properties
protein length:270 AA
molecular weight:30055,5 Da
isoelectric point:6,31
hydropathy:-0,39
Representative Protein Details
Accession
7PxDe
Protein name
7PxDe
Sequence length
270 AA
Molecular weight
30055,46940 Da
Isoelectric point
6,31052
Sequence
MVPKVRDWTARFLFGGPRSTSKLIGVCIHTTENDPSTPAENVANYQINSQSGSYHTLADRQGILRENTADWITWSTGNQGNTLLMHLSFVARASMTRAQWLAEDAMLRNGAWEVAQWCKKFGWPVRHVDVAGLPGITTHNATRVWGSTDHTDPGPNFPWDVFLSYVNQEVNGGATPAPTPTPEEDNTVMALLTGVSATALDIVRRGVTTLVTPLQSIINPKKSYLITDLVRFIDATAWENRVYLRELLREQGKNPDTIRDEAIKRDRGEA
Other Proteins in cluster: phalp2_17457
Total (incl. this protein): 7 Avg length: 267,7 Avg pI: 6,52
Protein ID Length (AA) pI
7PxDe 270 6,31052
7Bcne 264 5,88422
7duZq 266 5,77509
7xIZf 242 5,74593
7zBhX 276 6,49626
8GYqK 286 9,11759
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_18569
7cxQw
 45 62,2% 180 1.843E-84
2 phalp2_32230
7h6JD
 19 38,2% 178 6.341E-36
3 phalp2_24741
6EXtT
 52 33,5% 179 2.854E-24
4 phalp2_31178
7Vvn5
 47 35,5% 180 5.262E-24
5 phalp2_14187
2G1Y6
 10 34,6% 173 1.280E-21
6 phalp2_18351
5t09q
 43 33,8% 186 3.627E-20
7 phalp2_11245
6EoH4
 30 32,7% 177 1.220E-19
8 phalp2_184
5Dm5y
 192 31,2% 189 4.099E-19
9 phalp2_13713
6Ajj7
 6 27,6% 188 9.363E-17
10 phalp2_9206
6KeHU
 4 29,3% 184 1.708E-16

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7PxDe (270 AA)
Member sequence: Q9MBI0 (270 AA)
1 270 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Corynebacterium phage BFK20
[NCBI] 		28358 Sasvirus > Sasvirus BFK20
Host [Brevibacterium] flavum
[NCBI] 		92706 Actinobacteria > Actinobacteria > Corynebacteriales > Corynebacteriaceae > Corynebacterium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AJ278322 [NCBI]
CDS location
range 20961 -> 21773
strand +
CDS
ATGGTACCAAAAGTTAGAGACTGGACGGCGCGCTTTTTATTCGGCGGGCCTCGAAGCACGTCAAAGCTTATCGGCGTGTGTATCCACACTACAGAAAATGACCCGTCAACCCCGGCCGAGAACGTAGCGAACTATCAAATTAATTCGCAGTCCGGTAGCTATCACACCCTCGCCGATAGGCAGGGGATCCTACGGGAGAACACTGCAGACTGGATCACATGGTCTACGGGCAACCAAGGTAACACGCTGCTCATGCACTTGTCCTTTGTCGCTCGAGCGTCCATGACCCGCGCGCAGTGGCTGGCCGAGGACGCTATGTTACGCAACGGCGCGTGGGAGGTTGCACAGTGGTGTAAGAAGTTTGGCTGGCCGGTACGCCACGTAGACGTAGCCGGGCTACCGGGTATCACTACGCACAACGCAACCCGCGTATGGGGATCCACTGACCATACAGACCCCGGCCCTAATTTCCCGTGGGATGTGTTCTTGTCCTACGTCAACCAAGAAGTCAACGGCGGGGCAACGCCCGCGCCTACCCCAACACCTGAGGAGGACAATACCGTCATGGCTCTACTAACCGGCGTGTCCGCAACGGCACTTGATATTGTACGCCGGGGCGTGACTACCCTTGTCACCCCGTTGCAGTCGATCATTAATCCGAAGAAGTCGTACCTCATTACCGACTTGGTGCGCTTTATCGACGCTACCGCGTGGGAGAACCGTGTGTACCTGCGCGAGCTACTGCGCGAGCAAGGTAAGAACCCCGATACCATTCGGGACGAGGCTATCAAGCGTGACCGAGGTGAAGCATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
Q9MBI0
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00015ff52d_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7PxDe) rather than this protein.
PDB ID
7PxDe
Method AlphaFoldv2
Resolution 85.23
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50