Protein

Protein accession
A0A0A0RMY8 [UniProt]
Representative
7PoVr
Source
UniProt (cluster: phalp2_18267)
Protein name
lysozyme
Lysin probability
93%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MQSRNSKNVKIIDVSHHNGTINWTQVVLDGVKGAYIKLTEGTSFLSKTAYQNYLGAKNAGLRVGLYFVHTFFFISLLTSYSKYCIL
Physico‐chemical
properties
protein length:86 AA
molecular weight:9682,1 Da
isoelectric point:9,67
hydropathy:0,06
Representative Protein Details
Accession
7PoVr
Protein name
7PoVr
Sequence length
86 AA
Molecular weight
9682,05710 Da
Isoelectric point
9,67388
Sequence
MQSRNSKNVKIIDVSHHNGTINWTQVVLDGVKGAYIKLTEGTSFLSKTAYQNYLGAKNAGLRVGLYFVHTFFFISLLTSYSKYCIL
Other Proteins in cluster: phalp2_18267
Total (incl. this protein): 14 Avg length: 74,0 Avg pI: 7,01
Protein ID Length (AA) pI
7PoVr 86 9,67388
13676 64 8,81800
2zD3 70 5,39853
3MC5K 69 10,39657
5Oths 85 5,34198
62Ltj 77 4,92012
6VwcQ 66 6,99963
6wrIN 91 4,66235
7aKqw 49 5,98517
7apss 49 5,98511
7aptD 86 5,37500
7tvwc 90 5,41269
7vdI4 68 9,51852
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27642
6tvgH
 33 45,9% 61 4.063E-17
2 phalp2_19101
1qxtp
 5 35,0% 57 8.955E-15
3 phalp2_26543
8b1WD
 4 30,6% 62 1.977E-12
4 phalp2_15198
D6Gl
 21 38,5% 57 2.716E-12
5 phalp2_29843
3w2Je
 17 34,4% 58 3.182E-10
6 phalp2_39406
4SFDj
 5 29,3% 58 3.182E-10
7 phalp2_23403
65WGS
 2 28,5% 56 4.372E-10
8 phalp2_38344
yov5
 2 30,9% 55 1.047E-08
9 phalp2_20800
5MUs9
 16 24,1% 58 1.827E-07
10 phalp2_7802
7u45P
 1 30,5% 59 6.010E-06

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 7PoVr (86 AA)
Member sequence: A0A0A0RMY8 (86 AA)
1 86 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage Mater
[NCBI] 		1540090 Herelleviridae > Matervirus > Matervirus mater
Host Bacillus megaterium
[NCBI] 		1404 Firmicutes > Bacilli > Bacillales > Bacillaceae > Bacillus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KM236245 [NCBI]
CDS location
range 145586 -> 145846
strand +
CDS
ATGCAAAGTAGAAACTCAAAGAACGTGAAAATCATTGATGTATCTCACCATAACGGCACAATCAACTGGACACAAGTAGTGCTAGACGGTGTAAAAGGGGCGTACATCAAATTAACAGAAGGTACAAGCTTTCTTAGTAAGACAGCCTATCAAAACTATCTAGGCGCGAAGAACGCAGGGTTACGAGTAGGTTTATACTTTGTGCATACGTTTTTTTTTATTTCCTTGTTGACAAGCTATAGCAAATACTGTATATTATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7PoVr) rather than this protein.
PDB ID
7PoVr
Method AlphaFoldv2
Resolution 85.28
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50