Protein

Protein accession
M1I899 [UniProt]
Representative
6W0re
Source
UniProt (cluster: phalp2_3913)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDNNYRARTDFIVVHSTKTKSNQDLNAKDITLLHRKEGFFHNAFHFIIKRDGTIEEGRPEDMSGAILPINQPLITNQNSIAIALVGGLADDGKSLDTNFTYLQYASLRELVKRLKKKYKVEVVGCRNAINSKSCMSFDVLSIVD
Physico‐chemical
properties
protein length:144 AA
molecular weight:16233,4 Da
isoelectric point:8,89
hydropathy:-0,32
Representative Protein Details
Accession
6W0re
Protein name
6W0re
Sequence length
71 AA
Molecular weight
7826,97720 Da
Isoelectric point
9,03713
Sequence
ITNQNSIAIALVGGLADDGKSLDTNFTYLQYASLRELVKRLKKKYKVEVVGCRNAINSKSCMSFDVLSIVD
Other Proteins in cluster: phalp2_3913
Total (incl. this protein): 12 Avg length: 138,0 Avg pI: 9,00
Protein ID Length (AA) pI
6W0re 71 9,03713
A0A4Y1NUH3 144 9,32343
A0A4Y1NSF1 144 8,90632
A0A4Y1NTF8 144 8,77455
A0A4Y1NV28 144 8,88653
A0A4Y1NV43 144 9,21829
A0A7S5Y9Q9 144 8,90652
A0A7S6C6Z3 144 8,90652
A0A6S4PG74 145 8,90645
A0AAX3ZVR2 144 9,37559
A0AAX3ZW61 144 8,88653
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25112
1plEg
 298 52,9% 68 3.312E-11
2 phalp2_9258
6ZeMl
 429 40,0% 80 4.714E-07

Domains

Domains [InterPro]
Unannotated
Disordered region
Representative sequence (used for alignment): 6W0re (71 AA)
Member sequence: M1I899 (144 AA)
1 71 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pelagibacter phage HTVC019P
[NCBI] 		1283079 Autographiviridae > Pelagivirus > Pelagivirus HTVC019P
Host Candidatus Pelagibacter ubique HTCC1062
[NCBI] 		335992 Proteobacteria > Alphaproteobacteria > Pelagibacterales > Pelagibacteraceae > Candidatus Pelagibacter >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC465901 [NCBI]
CDS location
range 8432 -> 8866
strand +
CDS
ATGGACAATAATTACAGAGCAAGAACCGATTTTATTGTTGTGCATTCAACTAAAACAAAATCTAATCAAGACTTAAATGCAAAGGATATAACTTTGCTACATAGGAAAGAAGGTTTCTTTCATAACGCTTTTCATTTTATAATTAAAAGAGATGGTACAATAGAAGAAGGAAGACCAGAGGATATGTCTGGTGCTATATTGCCTATAAACCAACCTTTAATTACTAACCAAAATTCCATAGCGATAGCTTTAGTCGGCGGATTAGCTGATGATGGAAAAAGTCTCGACACTAACTTCACATACCTGCAATACGCATCTTTGCGTGAACTTGTAAAAAGGTTGAAAAAGAAGTACAAAGTTGAGGTAGTGGGTTGCAGAAATGCAATTAACTCTAAATCGTGTATGTCTTTTGACGTACTGTCGATTGTTGATTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0002b264d5_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6W0re) rather than this protein.
PDB ID
6W0re
Method AlphaFoldv2
Resolution 80.76
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50