Protein

Protein accession
PU19 [EnVhog]
Representative
2AeOK
Source
EnVhog (cluster: phalp2_10644)
Protein name
PU19
Lysin probability
63%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
VANKKGFDISHWNGTVFWIDVPDEYCWCYIKSTESDDFQDELFPQHWLGAYQENKLRSPYHFWRYAKTPKENVDNYYSYVREQGLGLGELPPILDVEDVYAPKSPWVLYEHILECLQRIEDSFQVEPWIYSAAWYWDEWVKTTRLRNYGLIVANYKTLLYPGIKPRMPKTGGWTEYKAWQHTDKAKIPGILGGSDGNIMPEEVFNEYSNPGPPPTTKIVKVLIPDGVEVIVEKI
Physico‐chemical
properties
protein length:234 AA
molecular weight:27375,7 Da
isoelectric point:5,11
hydropathy:-0,53
Representative Protein Details
Accession
2AeOK
Protein name
2AeOK
Sequence length
229 AA
Molecular weight
25396,71110 Da
Isoelectric point
6,59039
Sequence
MPYSIGIDVSHWQGDIDWKLVAQDGIDFVYAKASEGTAITDAMFAKHAAGARAAGLPFCAYHLYRDAADPVQQAIHFTRIALAASSDWMPPMLDFEDDKAKKLGEPLALRVLRCAQEIEARWLRRPLIYTSAYYWKKLCANSPALAEHPLWAANYTTANEPLLPTPWKSWTVWQHTSKAVVWGIKGGVDRNRAKPGFVNDGGEVPRFVELTVNEKSALDLKAALDAGLT
Other Proteins in cluster: phalp2_10644
Total (incl. this protein): 60 Avg length: 221,4 Avg pI: 6,06
Protein ID Length (AA) pI
2AeOK 229 6,59039
10Azj 209 4,70578
10Czh 209 4,70578
149cg 224 6,11624
16G29 206 4,80849
16MB4 213 5,35619
1Jp4A 162 8,53228
1Jwy6 190 8,83102
1axoQ 191 8,50849
1dzL7 208 5,12997
1gN0W 254 9,26283
1ihsL 242 8,65251
1lTKz 218 4,45756
1lqam 231 6,70577
1onyQ 260 9,58537
1otBX 253 5,84961
1ps6l 298 6,23162
20M5M 205 4,13341
244Lr 204 5,22051
285hR 190 8,84830
2TOmx 210 4,70578
2TZiH 210 4,70578
2Um1n 210 4,70578
2Yu01 191 9,13802
2t8DA 215 4,70601
3X56e 231 5,03704
3d4eP 144 7,92479
3eJB 228 6,41356
3hzgH 267 5,79197
3nnKz 213 6,96843
3yUqe 233 4,87272
4ECeq 185 4,37282
4Eqa0 241 5,06625
4GNrY 213 6,33149
4H3ob 261 4,78001
4JuO7 202 4,40374
4JyGQ 217 4,38100
4LMx4 247 4,71664
4N2R3 248 4,66014
4SE5p 257 4,14955
4fr7p 223 5,24746
4gJxe 167 7,82622
5Bi4d 231 5,41632
5nCkZ 245 9,59169
5nJVa 254 9,12867
6OS0W 198 4,53941
6VY3Z 216 5,51466
6x46w 216 9,29662
7FWda 228 6,06861
84dpa 241 6,42772
86Luw 228 4,18343
86Lx4 207 5,00436
870mF 219 4,75404
871pc 217 4,41113
8a7GS 206 6,52400
8iRYp 262 5,05301
DFfo 211 5,53341
Zleo 209 4,70578
nLMW 253 9,25897
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39912
1jXPT
 300 45,9% 187 9.822E-71
2 phalp2_20360
2RVWF
 69 35,9% 189 2.359E-60
3 phalp2_36157
6TiaL
 25 40,2% 194 4.424E-60
4 phalp2_26214
jZqY
 82 32,6% 184 1.029E-55
5 phalp2_35314
79Mal
 26 32,6% 236 2.380E-54
6 phalp2_32129
6Dieh
 5 38,5% 192 8.356E-54
7 phalp2_5862
5yfd0
 6 33,6% 214 1.930E-52
8 phalp2_5615
4g2xP
 40 36,9% 195 3.616E-52
9 phalp2_26909
4r87F
 36 32,3% 207 2.365E-48
10 phalp2_29268
hFI3
 21 36,9% 184 3.977E-47

Domains

Domains
GH25
Representative sequence (used for alignment): 2AeOK (229 AA)
Member sequence: PU19 (234 AA)
1 229 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
PU19
Method AlphaFoldv2
Resolution 91.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2AeOK) rather than this protein.
PDB ID
2AeOK
Method AlphaFoldv2
Resolution 89.98
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50