Protein

Protein accession
8K2tl [EnVhog]
Representative
5kP
Source
EnVhog (cluster: phalp2_39679)
Protein name
8K2tl
Lysin probability
98%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
LKKQLKNLTKEAIKLNKLIKTVSALALSLGLAFSFVAPSYASSLPSVDFIDVSHHNAENGLPLSFYQTIKGSGVQGVVVKVSEGSYYVDPAASVNIANARQAGMIVNAYHFARYTSNFAAKKEAIWFDKKLQLVGFDKKKDGYVTIDVEASGLGTASQVTEYTNTFIKQMKALGYSRVDLYTGSYYYNGQLIPSKLVVNKPWLASYPANPVKNKPTANFTNGKGAWQWASDYKFIGMSRYGNFDVSEDYAGKYTKKTSSTQVVTKGVGTIKVVSLVDYMKSKGMNASFSNRSKLATAYGIANYSGTQAQNLALLEKITTGTPVAKSNTSNSKLTTSNSKSFASSSLKTSTYKVKSGDTLSEIALKYKTSVLKLVSLNKLKNPNKLYVGQKLKVPAKTSVTKKAASKTYYTVKKGDSVSKIAVKYKTTVSKIKSLNKLKNPNRIYVGQKLRVR
Physico‐chemical
properties
protein length:452 AA
molecular weight:49374,2 Da
isoelectric point:10,01
hydropathy:-0,31
Representative Protein Details
Accession
5kP
Protein name
5kP
Sequence length
372 AA
Molecular weight
40634,10350 Da
Isoelectric point
9,96683
Sequence
MGKYHRRKRATLKKIIDGLIAEALTIALVLSFVAPVHAAPKVDFIDVSHHNAQGGLPLSFYQTIKVSGVNGVVVKVSDGTSYIDPAASVNVANAKASGMAVSAYHFARFTSVSEAKTEADWFDKQLKYVGFDKLKDGIVVVDVELPTASKATLTDATNAFTSEMHQLGYPTVDLYSGSGFYSSHLDADKLSISQPWLARYNGGKTEPVWRNGKGAWQWSSGYHFNGIGGSFDVSQDFAGKYASRYVAPNATAPKKVKKIGSVSLVNWLKQHKKAWSYSERSTLAKSYGITNYSGTAAQNIALLVKLKSGVKPAKNPKAVKKAVKKVKAHTYTVKRGNTLWGITRAHKTTITHVKMLNHLRSDLIRPGQKLKY
Other Proteins in cluster: phalp2_39679
Total (incl. this protein): 52 Avg length: 417,5 Avg pI: 9,82
Protein ID Length (AA) pI
5kP 372 9,96683
2G1EI 348 9,93266
2G1Ov 428 9,88773
2G28U 344 9,95729
2G2hw 415 9,62502
2G2iO 423 9,82809
2G2pd 428 9,92576
2G38R 432 9,80289
2G4Qf 392 9,60097
2G6Hh 399 9,53992
2G6Nm 395 9,77716
2GacN 416 9,39725
4Lhfw 448 9,39274
4MCnv 445 9,52941
4MMFj 448 9,69716
4j5Qu 390 10,09802
5hRmi 449 10,01486
5hUGG 426 9,96045
5hWqA 385 10,19730
5hYEL 388 10,07191
5i2Ym 437 9,85659
5i2gu 451 9,90603
5imk1 417 9,87928
5indR 449 9,93814
5ipKt 325 9,82197
5iqrg 425 9,90217
5iqz4 431 9,99146
5tSFP 432 9,87225
5tw8J 366 9,90358
71PHH 512 9,57570
71PHx 430 9,75531
793ba 437 9,90823
7JoP2 398 9,67853
7cRBy 344 9,99719
7dIOQ 438 9,98875
7dsab 435 9,79831
7ecaY 430 9,49008
7k0sj 449 9,97379
7krWy 432 9,74042
7l5VL 416 9,97321
7l5X5 335 9,98527
7poWj 428 9,68446
7td5n 333 10,03620
7vJTt 465 10,09551
7y8q2 376 9,70844
7zDtG 438 9,99868
8K2tk 451 10,01756
8m9IJ 444 9,28275
8maps 499 8,94236
aXmf 428 9,80598
l8Vt 437 9,96883
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9283
7cTgF
 101 32,2% 332 2.742E-59
2 phalp2_17635
6JmE3
 482 27,6% 391 8.516E-45
3 phalp2_26548
858CP
 728 27,7% 339 2.870E-40
4 phalp2_17042
7nSW4
 41 26,2% 339 6.758E-36
5 phalp2_30714
7hCUl
 46 33,7% 252 2.280E-35
6 phalp2_7780
7iNFi
 6 30,3% 247 4.113E-30
7 phalp2_22096
5ZSom
 2292 25,8% 360 8.318E-29
8 phalp2_37990
5tY12
 7 29,9% 237 5.521E-27
9 phalp2_36983
8LseV
 77 23,8% 419 4.155E-23
10 phalp2_7408
4FRdP
 29 24,4% 344 4.155E-23

Domains

Domains
Disordered region
GH25
LysM
Representative sequence (used for alignment): 5kP (372 AA)
Member sequence: 8K2tl (452 AA)
1 372 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5kP) rather than this protein.
PDB ID
5kP
Method AlphaFoldv2
Resolution 86.20
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50