Protein

Protein accession
625Tr [EnVhog]
Representative
8uHT1
Source
EnVhog (cluster: phalp2_29675)
Protein name
625Tr
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MEWIRGNFYLSAEQSDNNARLIWNYLKQKGWSKEAVAGMLGNMVHESSVNPEIWESLIVDYSRGYGLTQWTPATKLFDWCGTDTPTPEQELDRIIYEADNNIQWFSNPEVSPIDPPISFTEFKTSTLDVRTLATYFLYYYEHPANPHQEQERGDSAEHFYNLLEGESCKIYPKRLTDNGILNNPLWYSDNPFYQSGYGLPNCTCYAWGRFYELTGERPTLSTGNADQWFGNTADGYDRGQTPLLGSIICFGYTGSLTGQGGHVAIVEEVNWETGDIITSNSAYGGAFFYTQALKKSDNWTWTPDAYVQGFIYNPIDFCQNGETPTPTPTKLEAWLLKAIKRKHYYRRKLCY
Physico‐chemical
properties
protein length:351 AA
molecular weight:40265,2 Da
isoelectric point:4,85
hydropathy:-0,59
Representative Protein Details
Accession
8uHT1
Protein name
8uHT1
Sequence length
411 AA
Molecular weight
45959,16340 Da
Isoelectric point
5,36233
Sequence
MWYAKPRNGYDLGSTESNSNANEIASIFASGGYSSLAIAAICGAFYQECNMNPWQWEDNYIQSSNSISPNFGYGFPQFTPATEYINVANTKGDIDINNNYSPNFSNQTGLATDGAAQCYFIIRHHIDTVDGWEHDNAQPYRNLLSPHISAADVDAALNMTLQNFKNGYDNNNIPYSIDAMEAAFVANYLRPNYTQIRNNFGSTYLTFARWFKSYFDGTPIDPSTAFVPRLTADGIRYSKWWYSNGNIFYASGFGLDVNNGNCTCYAYGRWGEIRNEFANLPSGDAGTWYESVVGFEKGATPRLGAIACYKSRSGNTNNPGHVSVVEEINGDNIVTSNSGWGGPFFWTANVSGSEGYIEPWMISVIHGVQKDYYCQGFIYLDKFIPPTPPTPTTKPSHHIKPYYYINIIRRK
Other Proteins in cluster: phalp2_29675
Total (incl. this protein): 45 Avg length: 355,7 Avg pI: 5,09
Protein ID Length (AA) pI
8uHT1 411 5,36233
13CSK 365 4,83560
13cDH 374 5,64317
1nmTw 364 4,63712
21qNB 295 5,59412
2oAvJ 346 8,04451
3GQRD 385 4,56158
3WJn8 363 5,77441
3nPzc 425 5,78328
3yp6S 333 4,90540
41qwd 359 6,44022
5K9NL 352 4,99873
5Km0F 349 5,86791
5LXXm 351 5,11724
5Mxsa 361 5,59497
5OiL7 334 4,42676
5PSnc 352 4,78001
5RdeA 334 4,56374
5SCJO 386 4,51281
5SinE 351 5,04704
5UVpK 351 5,12519
5UkBD 352 4,98878
5XRi2 352 5,00515
5Xt7b 351 5,06216
62uZX 347 5,82772
6a2ie 334 4,51611
6cj60 334 4,83077
6ieGJ 386 4,55334
6kBrr 351 4,91017
6mo79 385 4,56851
6nVa 364 4,38140
6ncUt 334 4,50201
6oLy5 334 4,91552
6pi0x 351 4,98372
6rcio 381 5,27514
6slgX 386 4,56158
6tdOM 334 4,45944
70oKH 334 4,73590
7N94v 365 4,62177
7UlF0 370 5,57428
84McJ 334 4,99600
87XJN 349 5,87229
8fvYn 351 4,91773
8s68I 334 4,71698
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4910
6agyC
 8 27,9% 405 1.064E-78
2 phalp2_25591
3VKKL
 30 26,7% 422 1.003E-75
3 phalp2_31678
3dOcb
 3 28,0% 278 2.221E-40
4 phalp2_23793
1c5Vo
 1 18,8% 340 2.339E-14

Domains

Domains
Phage_lys2
CHAP
Disordered region
Representative sequence (used for alignment): 8uHT1 (411 AA)
Member sequence: 625Tr (351 AA)
1 411 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257, PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8uHT1) rather than this protein.
PDB ID
8uHT1
Method AlphaFoldv2
Resolution 80.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50