Protein

Protein accession
5hXUL [EnVhog]
Representative
2t2H8
Source
EnVhog (cluster: phalp2_27081)
Protein name
5hXUL
Lysin probability
99%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MFSVGGTVASMAKQFKADAAINFNYANTDDGIPIGRVIHEGKVIVSDIPKTIPREELYMSADGSLHIGKAPVGSKWALEGSPRLIHSGKDIIQESIKRDQLGSDVWSRPTYRTAVGLRDSKTLVVVRTRKEIELSTLVDIMFQLGCKDALNGDGGGSSYFFPEDSGWGRKLGSGLMIKTKTSGDETKVKKLIALCDGHGMETAGKRTPIGINDKETGANFMHENEFNRSVVKHLDAHLKRCGFDTLLVAPTDIDTPLSNRTALANSKNADFYLSVHANAVGNGEWNNTRGIETFHYTKASEASKKYASIIHKYLIGGTKLPDRGVKSADFYVLKETKMPSVLVECAFMTSKEDAALLLTDAYRKECAEELAKAICEMFSVSYVTESKGNQEPITPTSPDNQVISPIKIDLINGDVIETVDGLVRNGVSFVEVRKAGNFFEAKVGYDSTTKKASLTK
Physico‐chemical
properties
protein length:456 AA
molecular weight:49733,0 Da
isoelectric point:7,61
hydropathy:-0,31
Representative Protein Details
Accession
2t2H8
Protein name
2t2H8
Sequence length
423 AA
Molecular weight
46448,59970 Da
Isoelectric point
6,99872
Sequence
MIFEFDPTKYRFAVEIGIPGKLERLDKIPRPRPNETIACAININVFDWVGGSDGYGEIEQDGVQYKPESKGFPSISFKDGKLTLGDLPGAQVGVGIPITLVIDGKIDIRNPSKLATGFTSRTAVGQKSNGNIVFVTQEYMTTSELAEYMKSLGCINAFQGDSGGSTGMYLNGKLYDQGRAIAAALVAYKKKLIAIDDGHGMETAGKRTPIFPGTNTFMHENEFNNAVAQLLKINLEKSGFDTLMVAPDNFDTPLKTRTDRANAAKADFYISIHANALTGEWGTQNGISTYHYSGSVEGKKAAEIIHRNMLQGTKLQDKKVQTANFHVLKYTKMTSVLCECAFMDNLAEAKLLLTGAYRQECADEICRGICEYYGVEVPKPSTAVGLIEYALSKGYITNEAYWLKKVLLDKDLIDLFTNIKKKG
Other Proteins in cluster: phalp2_27081
Total (incl. this protein): 4 Avg length: 418,8 Avg pI: 6,81
Protein ID Length (AA) pI
2t2H8 423 6,99872
2Aaim 421 6,44619
2sQs1 375 6,19962
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30746
7yYs5
 21 38,8% 319 3.566E-72
2 phalp2_10364
1GIkp
 11 32,8% 298 3.393E-36
3 phalp2_35934
4YgQr
 6 31,1% 270 9.446E-27
4 phalp2_2076
2XPoB
 214 28,2% 290 3.066E-26
5 phalp2_12438
niO9
 5 28,8% 347 5.520E-26
6 phalp2_12440
ocDt
 3 22,4% 397 8.353E-16
7 phalp2_34472
4H20R
 2 24,7% 335 1.477E-15
8 phalp2_35751
4e0HH
 1 23,4% 366 3.468E-15
9 phalp2_23346
5BfRI
 1 24,5% 269 3.365E-14
10 phalp2_21710
3lk0z
 20 22,8% 285 2.350E-12

Domains

Domains
Ami3
Unannotated
Representative sequence (used for alignment): 2t2H8 (423 AA)
Member sequence: 5hXUL (456 AA)
1 423 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520|PF09992

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2t2H8) rather than this protein.
PDB ID
2t2H8
Method AlphaFoldv2
Resolution 89.12
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50