Protein

Protein accession
5K5I9 [EnVhog]
Representative
4hTzG
Source
EnVhog (cluster: phalp2_15834)
Protein name
5K5I9
Lysin probability
98%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPKIFLSPEDRASNAYASEALWNGHTTNEKEQMGRCADYLEIALKRCGFEVINAQYGNMYDRVRASNKWPADLHIALHTNGFNGKVAGTRVHCYPSEKSRAIGRLIQDRIAPMSPGASERLIEDTRLYELRVPTMPAVLPEFGFHDNPEEAQWLIDNMEAIAEETCKAVCAFFDMPYIAPDKQLDVEPEPVPDSGTIYRVQVGAFRKKENAEAYLQKVHEVLPEAFIVVG
Physico‐chemical
properties
protein length:230 AA
molecular weight:25917,1 Da
isoelectric point:5,23
hydropathy:-0,39
Representative Protein Details
Accession
4hTzG
Protein name
4hTzG
Sequence length
236 AA
Molecular weight
25791,57660 Da
Isoelectric point
5,62367
Sequence
VKKSVYLSPSTQEHNRGYGGYGTEEQRMNEVADVTQQALERHGLTVYRNKPEWTLQQVVADSNAKRPDVHFAIHSNAGGGRGCEVYCHRFGGGGEKLARAVYEELSPLTPTSDRGVKEGYNLFGPGVHLYELAETNAPAALVEIAFHDNPDDAQWIISHIEAIGTALAKGILNYFSITYMDDSPDLASGLKTLQEFGIIRSPEYWEQNAAKGKTVAGEYAAILIQRVAALLLKGGI
Other Proteins in cluster: phalp2_15834
Total (incl. this protein): 686 Avg length: 231,9 Avg pI: 6,80
Protein ID Length (AA) pI
4hTzG 236 5,62367
1030j 197 5,39581
10z4s 237 5,91406
14Wu6 219 6,31319
14XCq 247 5,70347
14udE 213 8,58869
167W4 223 9,06898
1G2GL 222 8,09422
1KvLe 250 5,23876
1KzbC 228 5,53091
1NAPo 239 5,82045
1NAum 263 5,05818
1Z9jY 181 9,11398
1Z9qx 181 8,95480
1Z9rS 181 9,41298
1c2Do 220 8,93540
1dRtf 281 9,34993
1dSeT 213 8,15133
1fCja 257 6,44431
1gCAn 244 6,40026
1gJ3O 251 8,50372
1gOXL 222 8,41565
1jCDS 220 8,62937
1jGJQ 241 4,96326
1k7he 220 8,41540
1k8ok 243 5,70791
1kfqx 228 8,34719
1kgCA 218 8,42784
1kh0I 262 8,76971
1l5z0 231 7,05590
1l96t 201 5,56644
1lFqf 233 7,00759
1lerp 247 5,24780
1liIc 247 5,98051
1mivk 265 6,21480
1nXdu 223 9,20088
1nXo2 219 9,02372
1nmmt 266 6,51997
1o5Cj 272 8,39825
1o5Nl 246 5,94180
1oDZN 245 6,00250
1ob4d 230 5,24342
20Blw 229 5,48004
20JcU 244 6,39623
29by0 226 5,47021
29qVS 226 5,21648
2G0k 246 9,37488
2GuDy 232 5,98960
2GvdT 233 6,23441
2Gyly 228 4,86590
2SM77 237 6,29091
2TZnT 226 5,38552
2V027 235 6,59403
2b9lv 223 7,65425
2bRh5 230 5,47754
2bXf9 220 5,03613
2ba8e 268 5,56752
2lW78 231 5,35306
2oyfn 219 8,70286
2sKda 225 5,00617
2tfgL 169 8,89401
2wkU 214 6,71197
33jHm 231 5,00373
35Erz 215 8,32404
35MfV 254 9,33368
38GPz 224 8,87602
38MEX 220 7,62742
39YAi 172 7,70529
3A4Ux 250 6,23986
3B7L8 263 6,94075
3GNT6 216 6,22838
3GQat 220 6,15279
3KN8k 217 7,58621
3KN9x 264 6,93989
3Lh4c 214 6,15807
3OPPL 228 6,60648
3OeW2 245 9,22976
3PQob 233 5,63015
3PStb 225 7,73285
3PXGW 223 8,30889
3PXLX 222 8,72343
3Q0wt 240 4,91733
3QDT6 227 5,73633
3QbPQ 191 5,94470
3QpaE 227 5,81721
3StbL 238 8,71221
3V9J3 225 8,74792
3a2Ll 245 5,16652
3caul 233 9,05531
3cxwN 232 5,98687
3eoVn 227 8,94281
3epZ2 218 9,16987
3gHiB 202 5,40632
3gdx9 218 5,57917
3ii8B 223 8,53834
3lgJT 266 5,58161
3mgq7 220 6,18990
3mlGO 233 6,45602
3nVBW 216 8,84218
3nlip 228 8,49701
3ntmK 232 8,90529
3nzTB 266 5,65908
3o2GS 220 5,17663
3pEjy 229 8,31934
3pbmS 214 6,31387
3piaN 266 6,38497
3rQAl 230 5,37989
3rfzd 233 6,39577
3sUva 218 4,53037
3sYgx 224 6,24276
3seN7 235 6,39833
3t6OD 233 6,42613
3t8wq 229 8,02917
3tF6v 214 6,31148
3tg6p 221 6,37378
3to03 230 8,02543
3triA 221 5,79095
3uil 226 5,71666
3ukmv 238 5,57161
3vIRy 274 9,13319
3vKr2 220 6,07941
3vyu9 268 8,11536
3vzuG 266 6,51894
3w9hn 266 6,64962
3wg6t 275 9,24253
3wi7C 227 7,56006
3xBuG 266 8,10285
3xUkV 245 9,00490
3xrUN 214 6,31387
3y2er 230 5,15185
3y92G 239 5,07358
3yEmR 228 8,02523
3yGQX 266 8,39270
3yQKI 220 6,15625
3yV9a 255 8,85088
3yWBM 260 9,24852
3ydeG 233 6,39577
3yy0G 266 7,57245
419nl 179 8,20871
41llp 213 6,08742
45B3V 223 8,58501
45ek 227 5,51591
45gmT 212 9,08458
46Kix 243 5,30668
4G3Ex 225 9,11649
4G76T 182 5,52153
4GLNT 219 6,31853
4GTLl 236 8,20890
4GUe8 217 9,11623
4H9oW 235 9,02681
4HgvR 227 8,52602
4Hp8G 226 6,17853
4Hyp2 232 9,02752
4Jux3 212 6,89078
4KhAP 243 8,88698
4KhS4 221 5,44480
4L4TD 254 5,87064
4L5x8 207 5,83887
4SD1i 203 5,87979
4StX2 246 7,64976
4Tief 230 5,96800
4U16U 259 6,19081
4USoi 245 6,00250
4VvUs 239 4,95468
4WmqC 230 8,15133
4XgD9 219 5,89713
4caeS 236 6,15051
4cafT 236 6,15051
4eZFA 249 7,77071
4jTS8 239 8,29877
4jXN9 224 8,75482
4jaSU 226 5,08558
4kpdW 241 4,68725
4kzWD 238 5,97090
4lF5U 236 6,66047
4m0Ec 219 7,72262
4qSHr 230 7,00981
4tN5j 234 9,21564
4tgml 217 5,85558
4uhuj 219 5,08666
4vJDS 191 7,04601
4wJ33 238 8,52493
4wWc2 225 8,79279
4xA1V 222 6,31682
4xOCc 253 6,52855
4xymI 200 6,29602
4yL36 199 5,79544
4z0LY 202 6,47018
4zm 235 8,57218
5BXAp 236 5,88525
5EvuR 224 6,65621
5Fbbj 218 6,22099
5K2Ip 219 6,59278
5K8f4 241 4,91404
5KLxM 262 8,14457
5KP87 220 5,46992
5KQze 275 7,54739
5KYa 226 5,51591
5Khxo 264 6,32171
5L2Rm 227 8,34822
5L3wt 262 7,02078
5L9PZ 218 7,58342
5LUrp 264 6,94075
5LZYR 235 6,18939
5LbAG 188 6,59079
5LiyL 218 4,56056
5Liya 252 9,32505
5LpA 219 6,08503
5Lsjp 216 5,85728
5Lxpt 230 7,52988
5M2Ri 233 6,19223
5MHzk 233 6,19400
5Mrsr 285 5,06432
5Mui8 214 7,03942
5NN7d 266 8,40328
5NN8B 266 8,40334
5NRQJ 214 7,62952
5NfLl 221 6,06122
5NolL 233 6,18376
5Nur0 143 8,80279
5OFHQ 237 5,55512
5OGRO 229 8,02910
5OJmd 216 7,98707
5OKWd 235 5,84961
5OKgj 216 5,98591
5OMVe 191 5,81852
5OPJ1 198 6,42044
5OSXW 259 5,17720
5OZ4m 227 8,39103
5OaYE 229 8,03316
5OhIc 262 6,07401
5OmYL 266 6,58630
5Omqa 233 6,39577
5OrD6 224 7,65129
5PFMY 223 6,24936
5PosE 268 8,41533
5Pryj 213 6,89954
5PuQW 217 6,53963
5PzKZ 230 5,19931
5Q8We 219 8,77494
5QP0t 264 8,10769
5QZPy 285 4,78467
5QzBs 228 8,55935
5R3Sr 233 6,32558
5R4lF 223 7,07511
5RD9v 224 5,78265
5RI3S 233 6,39731
5RK5d 263 8,42771
5RORt 227 8,02910
5RPtG 222 6,43158
5RVxn 233 6,32751
5Rb0L 221 6,58618
5RmN8 232 5,48021
5Rsiy 229 6,93898
5S6w2 223 6,57970
5SA7U 283 5,52847
5SEs0 243 7,97888
5SKSn 264 5,97784
5SMeh 224 8,12219
5SOu4 214 7,07443
5Sfef 198 8,91200
5SojJ 217 5,97380
5SzIM 216 5,38307
5T03K 212 6,43800
5T8Rg 222 7,57427
5THbx 220 6,13198
5ToMw 229 8,95906
5TsRE 336 9,21519
5Txgq 285 4,85402
5U6R8 219 8,79157
5UAKW 290 4,86743
5UHOb 214 6,38912
5UkFv 266 8,60777
5Uo0R 190 4,63115
5UrM8 230 5,13378
5UygP 165 7,63566
5V6Zr 268 8,10285
5VLLy 230 8,85217
5VT5q 223 5,99352
5VUZJ 214 7,03652
5VlZE 214 7,07420
5W3mi 230 8,95751
5WAFX 233 6,19400
5WHJl 214 6,50661
5WU3X 266 8,11252
5WVzy 216 6,52184
5WX89 221 6,89306
5WeRA 268 6,20769
5WqQ5 285 4,94808
5Wqyd 237 5,84716
5Wtos 228 6,93722
5Wtxy 233 5,13480
5X1FF 268 6,93950
5XBy4 230 5,09660
5XPWq 221 6,15279
5XQdt 213 5,62794
5Xg27 223 6,08606
5XogQ 262 6,07713
5Xuxv 233 6,18587
5YEcb 336 9,44077
5YIkC 266 6,16864
5YQn2 266 7,55887
5YUH6 266 8,60152
5YZ94 241 5,01709
5YbuE 214 6,25538
5YgN7 214 7,03652
5Yjmj 229 8,02917
5YlUM 219 6,43960
5YyLV 227 8,56541
5Z9ZK 266 6,98673
5ZAKp 231 7,09063
5ZIRU 206 9,53650
5ZY50 222 6,54100
5Ztfi 283 5,04750
5Zze3 216 5,59542
5dHfS 230 8,58114
5dL2C 227 6,90670
5hRNy 225 7,01577
5yM2 228 6,12533
5ypV 231 5,99961
600lN 218 8,42784
60OGl 220 5,96107
60X4z 266 7,57962
60YxD 233 6,01632
60dQm 222 6,38730
60n7j 224 5,99233
60qcG 232 5,14821
61eJt 221 5,36261
61lFN 214 6,42760
61x2L 269 5,81533
626WO 336 5,11195
62UqH 224 5,99875
62lrV 243 8,00789
63DrL 216 5,97448
63Nl6 266 5,28588
63XxQ 223 8,97685
63YEV 224 6,30705
63Zef 262 6,70970
63cmH 222 8,14611
63eQF 243 7,51147
63ivf 234 5,58349
63mzc 216 6,22838
63uBQ 260 6,22690
642f0 264 8,97653
64GP2 229 8,33500
64ioe 224 6,57999
64wZt 216 5,97607
64y38 216 5,39274
65A7F 214 6,45523
65BXQ 284 4,97878
65EDs 231 6,94524
65GAT 220 6,15279
65GP0 214 7,07386
65VSz 220 7,68079
65XL5 266 7,57001
65XL6 256 6,21230
65ivM 230 8,73606
6672Q 224 6,09021
66A1f 220 8,79170
66JHF 262 6,47745
66i0 215 5,26559
66oBh 232 5,37989
66ql6 230 6,23833
67D14 262 6,56601
67ZlV 225 6,57646
67gqd 275 7,56950
67zc3 214 6,45676
68ANr 222 6,45943
68GaM 218 4,56056
68IsX 229 8,32527
68MfJ 216 6,52474
68RwZ 218 4,51139
68Uqq 230 8,02162
68XyJ 332 9,21532
68lu7 233 5,85421
68oIz 220 6,06741
69X0C 216 5,99290
69bCg 224 7,68460
69pYb 223 6,52332
69qfZ 266 8,10775
69uog 233 6,66292
6PFFO 212 6,30472
6PsSs 188 5,76191
6PvPw 237 6,00347
6Q2rt 240 6,53571
6Qv67 223 5,27366
6WXJI 188 5,85433
6WXZA 188 6,22151
6WYb1 202 7,69471
6WZHq 201 7,71575
6XpMY 188 5,84506
6Xs3i 188 7,70262
6YVkC 214 6,31148
6YzX7 266 7,61531
6ZX7F 229 8,31579
6aF8t 222 8,65361
6aMhV 266 5,96948
6aa4S 219 8,78312
6adY7 232 4,91591
6af64 224 6,58329
6axAx 266 8,40927
6bNEn 221 6,20286
6bSYr 233 6,66292
6bbTN 262 6,41192
6blrJ 237 6,18723
6bzdm 220 6,15040
6c7Wc 275 8,57444
6cYC3 221 6,64837
6caes 276 8,38045
6cmax 221 5,78953
6cn6V 232 4,93399
6d8Jd 216 5,97988
6dFDQ 268 6,93313
6dFQI 214 5,17396
6dLsB 264 8,10285
6dS4P 232 4,98332
6dTvA 266 8,36356
6dpyr 266 6,94075
6drX6 224 5,47248
6dwsR 268 8,41017
6e9S2 221 6,06224
6eQCZ 217 8,12284
6eS6B 224 6,33780
6elrv 263 8,43319
6evYk 223 6,22901
6f4ax 231 6,53241
6fDHW 240 6,13028
6fIqW 233 6,18587
6fgis 358 7,07204
6fkvn 216 5,38307
6g2Ny 223 6,24703
6gEXY 233 6,39731
6gMpp 238 5,70467
6gPpS 218 8,42152
6giZP 216 6,52645
6guM3 220 6,17268
6hGHo 224 5,78265
6hIBM 214 6,50405
6hJDR 214 7,61372
6hdwj 210 5,66443
6hl1Q 266 6,94075
6hl2u 232 8,85991
6hrZR 214 6,50718
6hu82 220 6,19155
6i0Gm 217 8,21993
6iOVe 223 6,58113
6iSMi 218 4,56056
6iaaf 275 8,42765
6ieCj 269 6,01234
6igTU 218 4,61546
6ih8A 262 5,28923
6ip1f 232 4,86760
6iqR0 232 5,25166
6j1oq 220 8,62202
6jXyK 266 8,60152
6jgIM 211 6,44710
6jtOW 206 9,26980
6k0ST 217 8,11781
6kCOr 233 6,66178
6kOBT 230 8,38871
6kWvE 233 6,01632
6kkix 262 7,15435
6kt4z 232 5,37875
6ktfE 234 6,20121
6kvHw 222 8,43403
6l8Wx 237 5,44793
6lGlk 222 8,14328
6lQP3 233 6,66178
6lS3Y 210 4,87272
6lSo3 230 5,07916
6lkAJ 233 6,01632
6llgJ 218 8,11781
6m9Io 221 5,66499
6mvMS 219 8,68932
6my4T 223 7,01805
6n99m 219 8,62208
6nJKa 227 8,50230
6nSDi 231 5,25047
6o7ds 220 5,95999
6o9qU 221 5,96329
6oFav 212 5,85359
6oLxA 214 6,50428
6oVZt 222 6,10521
6oaHh 188 5,19903
6olhZ 166 8,89324
6omqC 235 6,00734
6pDjN 224 8,60480
6pE85 289 4,97815
6pRaz 228 5,77538
6pcQU 220 6,06741
6pfDf 220 6,43039
6pikF 264 8,39838
6pu3S 227 6,94347
6py7m 216 6,22838
6pyhi 243 6,89203
6q0Ep 224 8,06533
6q4AU 213 6,71339
6q5vW 224 7,58689
6qjlJ 225 5,95510
6qq9E 336 9,44077
6qtfn 266 8,40418
6qxBS 229 8,31573
6qxRq 230 5,07768
6r0fP 233 6,19428
6r3KQ 266 8,10479
6r5UY 238 5,56621
6r6b5 214 7,03180
6r6hn 175 8,59114
6r8D7 233 4,91591
6rDGa 214 6,50729
6rIpt 221 6,44369
6rcis 214 6,50775
6rpNS 233 6,66292
6rum8 233 5,85529
6rxcc 237 6,00734
6rzaf 233 6,66292
6s49l 222 6,51934
6sA1d 283 5,04926
6sCW0 285 4,94092
6sQAm 224 6,17643
6sXXO 262 6,70464
6spJq 207 5,06784
6t50z 218 6,93972
6tTrE 233 6,01632
6tZoR 235 5,85074
6teeE 231 6,23702
6trLq 224 7,02339
6uNYu 214 6,25333
6uVqA 221 6,94859
6uenh 218 8,42152
6ug1A 285 5,07893
6ugqH 266 8,41520
6v2nx 214 6,50661
6vAY1 278 8,08880
6vI69 235 6,00825
6vKXM 216 5,30174
6vKou 225 8,89072
6vaPm 266 8,10285
6vbbl 223 5,98733
6vmIm 229 8,03303
6w8Of 225 6,57470
6wGJz 191 5,91992
6wzmw 285 5,07967
7095q 266 8,07223
70n9E 227 8,32043
70qkm 237 5,84711
71JjI 232 6,61045
71jVH 223 8,48773
71oou 229 5,89030
73fb 226 8,91213
77JYN 236 5,82477
78PGw 224 8,54175
79ohG 219 5,71308
7EagJ 232 5,59400
7G5s9 239 5,53688
7G8EI 226 5,56268
7HtFS 219 6,08503
7J5lG 223 5,44281
7J5md 219 6,30875
7JqRq 231 6,65291
7KjwM 232 7,70500
7NqRT 214 7,06966
7UkBd 266 8,39270
7UkZi 222 6,82542
7VXAe 224 5,13867
7VYC7 217 8,39670
7Vma0 266 6,16864
7Vmwd 217 5,60918
7WFsW 222 6,17268
7WHGM 266 6,64740
7XCTE 214 6,18473
7Y5W7 285 5,00646
7YR7O 268 6,81894
7YTL 245 6,00250
7YXCC 220 8,16133
7Z5ia 214 7,06727
7Z6Op 258 6,31768
7aci 198 6,29295
7bfTP 235 7,09552
7oVjo 209 5,97119
80Rrn 285 4,88687
80hNn 265 5,50397
81tdh 242 5,07239
83Lu6 218 4,73630
83Me7 266 8,18286
83UPs 221 6,15625
83UuB 266 6,52162
83WCI 206 7,11126
83vVM 223 5,44730
84LRc 218 8,11781
84MNj 230 8,57928
84MaN 264 6,99503
84N1P 220 5,86274
84NVo 214 8,10833
84Nco 252 9,15685
84Uom 218 6,87311
84cJh 222 6,10533
84po3 260 9,30957
84xLK 191 6,97553
84xw7 232 5,13378
85DsB 216 5,77032
85acx 228 8,78512
85b6n 209 5,83631
861Lr 214 6,45864
86roV 223 5,45628
879cJ 233 6,39731
87wYG 232 5,47578
87ypL 217 6,94694
87ytV 235 7,59695
88niu 214 6,46068
897NG 191 6,97803
8Zlu 219 5,77737
8bC3A 275 8,09344
8cGG8 239 9,00896
8cJo9 268 6,58516
8cyR7 230 8,74303
8d0A 236 6,99918
8dcBy 277 5,24575
8dfSO 214 6,14955
8eLtP 236 5,33101
8f6Tr 218 4,56056
8f7Zw 217 6,10408
8fAXY 247 8,39805
8fAi 215 6,43749
8fN8J 214 6,14648
8fPOV 230 6,09276
8fdB1 191 6,36139
8gkr7 229 8,31579
8iKI7 213 8,46207
8iKoP 214 6,45653
8k1VX 218 8,80027
8kW9U 214 6,75392
8lUvE 212 7,63287
8lWG1 241 5,14321
8lbO9 266 8,61486
8lcrf 273 8,66895
8le66 233 6,66292
8llcH 265 7,63225
8mYIX 266 7,59309
8nOET 230 8,74303
8ov1K 213 6,45653
8pATS 218 4,46376
8pCI6 214 6,50775
8pYv3 191 6,28522
8prLW 203 7,61213
8r505 214 8,09989
8s66f 218 4,62876
8tJRQ 191 6,36338
8tJYa 191 6,57357
8tnMu 285 4,78956
9um1 288 9,38951
9v6n 219 6,08697
BNBU 216 6,93853
BNyt 230 9,30087
EGSR 213 6,31239
JP73 265 6,94143
JT3B 210 5,67739
NMtK 210 8,39109
OVur 197 5,70643
PFjv 245 8,25423
QAhe 220 9,18534
R9D8 243 9,00657
R9WX 226 5,35102
Tg6N 231 5,00543
Ti2A 223 8,24759
UOIH 224 6,24782
UORc 206 7,85040
ZitW 229 6,44329
ZjwZ 233 5,51858
Zlha 226 5,21648
abjr 226 5,19499
acE4 211 5,82176
afSA 222 5,99716
agdz 219 6,43675
agrN 218 6,45665
fAdI 238 5,36301
fEed 190 8,70189
k3x4 248 5,19926
ocMH 224 6,22912
on6I 194 8,71214
wyaK 226 5,09876
xsk0 220 8,99194
z2U7 229 8,36273
z3FZ 226 6,22702
z7B7 233 6,39731
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27984
103o3
 18 47,7% 178 2.068E-59
2 phalp2_17555
5USO4
 4 39,0% 192 1.221E-51
3 phalp2_3831
6vxOH
 1 29,7% 188 3.845E-50
4 phalp2_12346
5s3L
 1 30,0% 180 2.730E-44
5 phalp2_1754
2GVcd
 17 40,4% 173 2.730E-44
6 phalp2_26880
4f46L
 1 35,2% 193 3.734E-44
7 phalp2_5244
8bLQV
 113 30,2% 205 5.580E-42
8 phalp2_36176
6WzQU
 47 28,1% 206 5.415E-39
9 phalp2_30465
4Uk3l
 3 31,4% 194 7.400E-39
10 phalp2_24413
4m1OU
 1246 31,2% 192 2.476E-35

Domains

Domains
Ami3
Unannotated
Representative sequence (used for alignment): 4hTzG (236 AA)
Member sequence: 5K5I9 (230 AA)
1 236 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4hTzG) rather than this protein.
PDB ID
4hTzG
Method AlphaFoldv2
Resolution 94.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50