Protein

Protein accession
4hlhD [EnVhog]
Representative
2cnxE
Source
EnVhog (cluster: phalp2_27050)
Protein name
4hlhD
Lysin probability
97%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKLKFIKILIIGGILLMPTKIIYLSKETEKALNEMVKEAIKENSELYGIEKALIKAIIEHESMNYVFAFRVDYKALKKQEWYNKLLDEKEKKDKKYYASYGLMQVLYGLAKSLGFNGTPEDLFNPMVNIRYGCKYLQRLKSAYRDIKDIIAAYNYGYAKKRKNGTYYNQSYVCSVYEKYKKYGGKL
Physico‐chemical
properties
protein length:186 AA
molecular weight:21859,5 Da
isoelectric point:9,51
hydropathy:-0,45
Representative Protein Details
Accession
2cnxE
Protein name
2cnxE
Sequence length
189 AA
Molecular weight
22072,40110 Da
Isoelectric point
9,60381
Sequence
MSKLIGVFILFFLFSFSINTEKTIKPVKKVNHFDQYDDIILENAKKTGITPYLIKAIIYCESYMVYNTNRYESHLRTAEWYTNLIPDEYKSNKLSYTSVGLMQILPGIAWLVGYKGPPEGLYDPKVNIYFGVKHLLNIIRGYRYQARVVSVWNGGHLSRKKDGTYKNQKYVDNVVRKYKKYKLEGINAI
Other Proteins in cluster: phalp2_27050
Total (incl. this protein): 19 Avg length: 185,1 Avg pI: 9,22
Protein ID Length (AA) pI
2cnxE 189 9,60381
1BQIm 175 9,80340
1Cnwi 176 9,75344
1E81e 173 9,53528
1PvMf 232 7,91074
1Qvsm 219 6,09259
1hPqL 192 8,98394
2cA26 194 9,15253
3LIdO 220 9,74087
4BcV0 180 9,71327
4HwHd 186 9,62418
4hHje 187 9,47577
4ipWh 196 9,78284
4iqez 186 9,25187
5E1ik 139 9,57151
5lAEV 165 9,07426
5mmuE 167 8,84817
hIIP 154 9,75782
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3406
3Pi2s
 331 34,4% 154 7.423E-41
2 phalp2_11114
5jcjr
 291 29,0% 179 1.899E-31
3 phalp2_36181
6Xpof
 3 25,0% 148 2.855E-29
4 phalp2_22364
ht2E
 5 28,1% 149 3.124E-27
5 phalp2_18812
1iUcj
 1 26,4% 140 4.449E-22
6 phalp2_2984
18TMj
 135 28,4% 144 1.133E-21
7 phalp2_25771
7CoqA
 3 27,5% 160 7.340E-21
8 phalp2_9329
7BCrF
 25 26,1% 176 3.478E-20
9 phalp2_20310
2k1Qv
 26 24,4% 131 3.332E-15
10 phalp2_4832
5l1Nn
 14 26,2% 145 1.559E-14

Domains

Domains
Disordered region
SLT
Representative sequence (used for alignment): 2cnxE (189 AA)
Member sequence: 4hlhD (186 AA)
1 189 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01464

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2cnxE) rather than this protein.
PDB ID
2cnxE
Method AlphaFoldv2
Resolution 89.13
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50