Protein

Protein accession
4MK3S [EnVhog]
Representative
7umqo
Source
EnVhog (cluster: phalp2_24845)
Protein name
4MK3S
Lysin probability
99%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
VTLNGYDISAYQGSLSPAAVPGDFVIVKATGGDGYVNPNFRAQVQAARNAGKLVGIYHFARDGYTAATAQSEAAWFIRNAGDLLDGSVLAVLDWEADNQTDVGYAKAWLDTVTAQTGVKPIIYMSFATIKAADWSSVANADYGLWEAAYVLGYQQINGYNPPAGLADIPYWSTRCMWQYTSVGRLPGWGDNLDLDIFYGDATTWAAYAAKVGASINPQSTTITPEADMPLTPDDAKLVAEEILNYDLVRQGDGQTGTTNLRALVQWFDNAVSNIVNTVDGHVDAAVKAIPAGSVSLTDAQVQSLADKLTASLPAANLALLKSKL
Physico‐chemical
properties
protein length:324 AA
molecular weight:34485,1 Da
isoelectric point:4,38
hydropathy:-0,02
Representative Protein Details
Accession
7umqo
Protein name
7umqo
Sequence length
348 AA
Molecular weight
37119,21440 Da
Isoelectric point
4,43847
Sequence
MTLFGIDVSSAQHGIDTGAVPSDIVMIKLTGGTGYVNPDFDAELAKAKADNKGVLAYHFYHEEYLEGTPDQEAQFFLSHVMPYLDGTVGVALDYEPTPTGRFNALDPAQSKAWCDIVHAQSGVVPWGYGPVSTIGAGLRSVSDAGYPIWAAAYTLGYQPIYGYTPPVGPLGVPAGMNVKMWQFTSSGHLPNWPNELDLNIFYGTRAEFDALCAVGGAINPQGYKPTPPSEDDGMSQAEVLEIQGFIDTLQTELQKSVGEVTQQLIQDQIRDLTAHVDASIQAALFASEKFDQKAGQDEGAVIINEVRANANMLVAIAAKNAPAVAAAIPADIAQAVADELAKRLTETK
Other Proteins in cluster: phalp2_24845
Total (incl. this protein): 6 Avg length: 338,7 Avg pI: 4,41
Protein ID Length (AA) pI
7umqo 348 4,43847
4LhMu 316 4,35054
4ME9u 340 4,46160
4MH5r 340 4,38691
4Tv32 364 4,43790
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16579
7zIOC
 8 42,7% 215 3.545E-60
2 phalp2_32821
2L8bh
 41 35,3% 232 2.293E-59
3 phalp2_8460
169H9
 3 38,9% 254 4.409E-52
4 phalp2_22096
5ZSom
 2292 33,7% 237 1.816E-50
5 phalp2_4660
4CJrS
 5 30,0% 236 1.016E-48
6 phalp2_4274
8cjfF
 9 33,9% 230 3.610E-46
7 phalp2_37341
8v6XY
 562 33,3% 237 4.917E-46
8 phalp2_27394
4HDMm
 9 34,4% 215 1.690E-45
9 phalp2_19044
1cI3q
 6 39,9% 218 5.920E-43
10 phalp2_12276
79roT
 46 36,0% 236 3.783E-40

Domains

Domains
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 7umqo (348 AA)
Member sequence: 4MK3S (324 AA)
1 348 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
4MK3S
Method AlphaFoldv2
Resolution 77.53
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7umqo) rather than this protein.
PDB ID
7umqo
Method AlphaFoldv2
Resolution 75.28
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50