Protein

Protein accession
4LP25 [EnVhog]
Representative
4MOEK
Source
EnVhog (cluster: phalp2_6008)
Protein name
4LP25
Lysin probability
98%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTRPVPQCALQFLKGAEAVRLTAYLDSAAVPTIGVGHTGPEVHLGMTITPSQSDAYLFADATKAATRLALMVKAEVIEALSEHQYAALISFVFNLGTPKSTLWGLLNARNFAAVPAKMMEFDKARVKGRLVELPGLYNRRAAEVALWKTADVAAATAMVQAVPPTPPSSYTRAADTPEAQGSLKPNSRSKSFIASAVTACAATAAPFVNQIQAGAQTVNKTLEPYIGGSEILQHVHENLTIGLAVLAVLTVVLVGLKNKGMS
Physico‐chemical
properties
protein length:262 AA
molecular weight:27609,7 Da
isoelectric point:9,23
hydropathy:0,21
Representative Protein Details
Accession
4MOEK
Protein name
4MOEK
Sequence length
247 AA
Molecular weight
26734,53170 Da
Isoelectric point
9,79141
Sequence
MTRPVPARARALIADYEKDVLTLYDDGVGIVTGGRGHVVPGGKIGTRITQRQSDMWFEEDLQIAAKRLERKIGAEVVAALGEGQYGAMVSFVFNLGTGGSSPEWKIWGFLRRKEFAAVPDQIKRFNRAGGKVLRGLERRRQAEVNLWLSDSPEEAHVPSSVTRIIPTPPAPEATVKPMVQSKTMWAGATVAVSGVAEGARQVQALVAPQAYYSEYLAKLGGIIAGVIVAAGIAIMVFRWLDARGAKH
Other Proteins in cluster: phalp2_6008
Total (incl. this protein): 54 Avg length: 256,4 Avg pI: 8,19
Protein ID Length (AA) pI
4MOEK 247 9,79141
16IXD 245 9,55346
1NDbG 263 6,37236
1hQ9W 250 6,29284
1rryp 249 8,02549
20FgF 254 5,85757
2SL4r 260 6,36775
2Sa5Y 254 7,80553
2cMUc 297 7,75792
3IvG 259 5,04465
3LWxc 261 5,07444
3MlVx 271 5,83528
3YMRV 255 4,93422
3aNLV 255 9,50962
3aOuT 255 9,42181
3g2fV 260 6,10913
3m0T 260 6,36644
43MtX 242 9,23614
46rPQ 244 8,51797
4CE3o 260 9,54230
4EXXM 271 6,19030
4GBaK 240 9,32466
4Jzyp 266 4,94149
4LHSW 246 9,51233
4OaDT 245 9,06595
4SVz7 262 9,19469
4SX2y 264 8,31689
4eETh 258 10,13251
4eQmd 258 10,13251
4f4TH 258 9,38210
4kx9z 244 9,84331
570ZJ 243 9,74480
5EYPU 239 9,51858
5HW3k 265 10,29568
5d1ys 244 9,58157
5tmNY 252 8,84650
5uzb3 254 9,68936
6EZ88 282 9,54379
6HU0c 262 5,70774
6KEdi 277 5,45844
6Nb9T 254 8,73058
6RZek 243 9,73481
6S5qI 242 8,97363
6WMlZ 282 8,82677
7hFtl 242 9,19895
7t2MS 243 10,03272
86MNp 268 6,05150
8b3nI 246 9,85259
OVx7 249 9,44173
hDzz 266 9,37649
hrtZ 269 6,13039
hyHR 242 8,97363
iCzF 265 5,91213
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2498
5GMvl
 297 28,4% 250 7.180E-49
2 phalp2_8792
2bBC2
 14 38,8% 152 1.430E-43
3 phalp2_40579
4SZ2W
 11 30,0% 223 3.255E-42
4 phalp2_10966
4MkR6
 70 30,8% 211 1.677E-39
5 phalp2_29738
1pBjt
 830 31,0% 206 5.842E-39
6 phalp2_19992
6T980
 5 27,0% 259 2.979E-36
7 phalp2_14481
4Lj5N
 23 31,3% 153 4.068E-36
8 phalp2_126
5jCCA
 637 35,0% 151 3.597E-35
9 phalp2_29201
77dZ
 15 30,0% 173 3.176E-34
10 phalp2_30676
6Q25R
 25 26,8% 212 1.102E-33

Domains

Domains
GH24
Disordered region
Representative sequence (used for alignment): 4MOEK (247 AA)
Member sequence: 4LP25 (262 AA)
1 247 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4MOEK) rather than this protein.
PDB ID
4MOEK
Method AlphaFoldv2
Resolution 74.86
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50