Protein

Protein accession
4Esph [EnVhog]
Representative
4Ezja
Source
EnVhog (cluster: phalp2_19688)
Protein name
4Esph
Lysin probability
86%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MLIADTNEFHPLINAEQYKSSREPDGTYHPVIIARATYSDTHVDNAYVSTINLARAAGLHIGHYGYLTAGGNPVSEGTFFARTILDHGGLKLGDSVWCDDEEGSGIQTPRAMNFLGAAHSVLHDALIDEGVYSGAAFWVAHLGSLPSGLHRWVASYGSADPKLAGEDLWQFADNRDVPGVQGPCDASIYKGTLDDWLKMVSPPATPSPTHIQEDNMLQYIAAGDALPITWPDGAKAVRLVSNSDPTKPVPVKIDWYITAPDTQVNVGYGNVVDVEIPGGRGATLHRSDAPGSETATADLGFIFTS
Physico‐chemical
properties
protein length:305 AA
molecular weight:32597,8 Da
isoelectric point:4,78
hydropathy:-0,19
Representative Protein Details
Accession
4Ezja
Protein name
4Ezja
Sequence length
296 AA
Molecular weight
31656,56590 Da
Isoelectric point
4,99265
Sequence
MIIADTNEFHPLTNSVAYRDAREPDGSNHPVVIMRATYSASHVDLAYPSSVRAARAAGLHIGHYGYMTASVDAATQGRFFAQTVIANGGLRIGDTIWCDDEEGAGNQSPRAVAFLAEAHNLLKDFLSDEGVYSGSAFWLAHLGEVPTGSHRWVAAYGQSDPALRGENLWQFTDGKVMAGVSGPCDASIFRGNLAKYLATFGAPSPKSDPSTYQEEPMLLNSGIGATPIALPTNAKSVRFFSNSDAEVKVDTRNGNSQDVHLTYDSADTVDVPDGINGFVAHRVDDGKNDVSFVINT
Other Proteins in cluster: phalp2_19688
Total (incl. this protein): 7 Avg length: 300,6 Avg pI: 5,32
Protein ID Length (AA) pI
4Ezja 296 4,99265
4E2oK 297 5,21932
4ETB7 307 5,82147
5JKR4 304 5,00038
6IRDd 288 6,07998
6VeDN 307 5,36301
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19875
5GUq8
 18 37,2% 220 3.642E-29
2 phalp2_9690
23WOG
 27 35,8% 212 2.287E-28
3 phalp2_25550
3zK3V
 3 35,5% 197 3.106E-28
4 phalp2_16973
870CF
 1 34,4% 203 2.237E-26
5 phalp2_1978
4EA8c
 6 30,0% 266 2.237E-26
6 phalp2_23128
4EkZf
 1 32,7% 235 1.111E-22
7 phalp2_10923
4EY3t
 12 31,3% 214 2.544E-20
8 phalp2_33074
4Ed1q
 2 23,3% 326 2.817E-19
9 phalp2_1137
5J3v
 11 28,2% 202 3.264E-13
10 phalp2_37813
4EL04
 15 23,7% 265 1.096E-11

Domains

Domains
GH25
Unannotated
Representative sequence (used for alignment): 4Ezja (296 AA)
Member sequence: 4Esph (305 AA)
1 296 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
4Esph
Method AlphaFoldv2
Resolution 75.57
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4Ezja) rather than this protein.
PDB ID
4Ezja
Method AlphaFoldv2
Resolution 86.12
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50