Protein

Protein accession
3sKuP [EnVhog]
Representative
2bNef
Source
EnVhog (cluster: phalp2_3229)
Protein name
3sKuP
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKKIADISKWQGNVVWAKAAAELEFVILRASCGISMDVKYLRNVEGCVQNGIPFGAYHYVKAGTAEEARREASYFVFCTEKAAKQPSFFIADIEYEAQTQMTTEAVCVAFLDELRKLGCKKIGLYINTRYKWAGAAIGMCDIVWIPHWGLNDGNIPADKYKPSCPHELWQYTSCGSLAGVNGSVDLSLLSGGKPLDFFTGVETIPAPDETEGSEKKMFTNIRLAEFALKVFDAKWVYWYGTYGNKCTQSKYESKAKQYPAHYTASRKNGYMKDIANGCTCADCVGLIKAFFWKNGDLNATPKYGANGCPDKGANSMFALCKESGPISSIPDIPGIVVWKSGHIGVYVGNGYTVEMRGFAYDCVKRKVSEGPWTHWGKLPASMLTYAADGTVSQPESTKKKLGDRLPLSKGAKGDDVKELQNALLALDQTLPKYGADGDFGSETQKAVAAFQAAKGLNQTGALDEATYKALTDALNAPKEPDGNVPDDTGNDPVRSFVLIVSGDEATLRKLFEQYGGTLAEVDSVTVG
Physico‐chemical
properties
protein length:527 AA
molecular weight:57330,5 Da
isoelectric point:6,37
hydropathy:-0,27
Representative Protein Details
Accession
2bNef
Protein name
2bNef
Sequence length
531 AA
Molecular weight
58513,31040 Da
Isoelectric point
4,91984
Sequence
MGKIADISHYQGDIDWSKARKELDLVIFRASVGSNADKKYLEYTAECGVPYGAYHYVKAGTAEDARTEARFFVECAHKAAKRPLFYIADIEYEAQTETTTEPVCVAFLEELRALLGNSVKIGLYINRKYKWAGAAIGMCDIMWIPHWGKNDGNVPEEKYQPDYYCDIWQYTSEGSVAGIDGDVDLNLLLGDKPLEYFTEGYVPDEMKGSESVMDSKFSGVPTNLHLVAWMIAAHVAKVVYWYGTCFYECTKSLYTRKKNQYSKYYTSARESGYMADIAAGKMCADCVGIIKGFFWTGGDPNGKNVYEANNCPDRSANGLFSLCKETGKISTIPDIPGLVVWRDGHIGVYIGDGETIELKGFAYDCERNDVGDGSWTHWGKLPPSMMNYVTDGASVPAPAKLKLGDRLPLKKGDKGDDVAELQTALKTLGFDLGTYGPKKDGIDGDYGTKTRNAVSDLQRTSDMKEDGVFDTPTYKALLNRLSPAPEPEPDTPDGGSAPAYMLIIEGDEDDLRKIQADHGGTLAAVDSVIMV
Other Proteins in cluster: phalp2_3229
Total (incl. this protein): 21 Avg length: 544,0 Avg pI: 6,31
Protein ID Length (AA) pI
2bNef 531 4,91984
21rdY 517 5,14367
38Jsm 555 6,40612
3TGdx 565 5,77930
3TOBm 522 5,36773
3vyQ2 576 8,10176
41fMp 564 5,98704
41i5B 564 5,69324
4L1Lv 565 5,53262
4L7Z2 524 4,98611
5NTvU 523 8,00847
5X4PN 523 8,03200
67H74 577 6,11846
6ZmhN 527 7,00315
6lsir 527 6,06673
6pQcv 523 7,76093
6pejU 572 8,10182
6vOt 573 5,81863
6wZi 545 6,33075
7DLj4 524 5,08689
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16073
3ZPs0
 22 36,9% 542 2.494E-130
2 phalp2_15784
3ZRUV
 1 27,9% 519 2.408E-72
3 phalp2_34377
4dm6y
 15 21,0% 579 4.030E-32
4 phalp2_4916
6k3vw
 208 23,4% 524 3.114E-30
5 phalp2_2377
7JCYq
 91 24,7% 505 1.325E-28
6 phalp2_19076
1kAmm
 2 20,6% 508 7.298E-26
7 phalp2_16855
1Jgdv
 1 21,0% 494 2.954E-17
8 phalp2_9994
3h23S
 34 20,3% 502 2.158E-12
9 phalp2_8926
3gaRh
 5 21,5% 516 9.691E-06

Domains

Domains
GH25
Unannotated
PG_1
Disordered region
Representative sequence (used for alignment): 2bNef (531 AA)
Member sequence: 3sKuP (527 AA)
1 531 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2bNef) rather than this protein.
PDB ID
2bNef
Method AlphaFoldv2
Resolution 85.53
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50