Protein

Protein accession
3mrc2 [EnVhog]
Representative
4dm6y
Source
EnVhog (cluster: phalp2_34377)
Protein name
3mrc2
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKTFGIDISRWQGDFDMAKAKTEGVKFVVIKGGGGDSGFYVDKKFAENYIAAKRLALPVGCYWFSKALSVAEAQKEAEYFLSSCLRGRQFELPVYMDVENRQMLALGKRKLTDIVKAFLDALTAKGYCAGVYSSKSMFADYLYDSELSSYPHWVAQWASACTYPGQYGMWQFGGEINKIRANTVAGVVCDQDYMLEDYPAMIKASGLNGFTKTEVKKMGTIKELVALAESEVGYLEKRSNSQLDDKTANAGDKNFTKYQRDMDAIEGFYNTKKQGFSWCDIFVDWCFVKVFGVEEALRLLCQPRKSMGAGCDKSAGYYKEKGRWFTTPEIGDQIFFKSSLYAFAHTGLVVNVDAHYVYTVEGNTSGASGVIANGGGVCKKKYERSNANIVGYGRPLWTAAEKVGVPSSPAAAAPVVKTVNVAIRQLSKGMKGNDVKTLQILLNAYGCDCGSADGDFGAKTEAGLKKFQSQFKLGADGIAGAKTWNKLLSA
Physico‐chemical
properties
protein length:490 AA
molecular weight:53719,8 Da
isoelectric point:8,81
hydropathy:-0,23
Representative Protein Details
Accession
4dm6y
Protein name
4dm6y
Sequence length
539 AA
Molecular weight
61750,15790 Da
Isoelectric point
5,08825
Sequence
MCERILGIDISVHQGDFPLDVAITQGVKFVIIKGAGGDCGLYKDSKFERNYLLAKQLKIPVGCYFYSRALDEYTALKEAEFFYENCLKGKSFELPIYYDVEDRAQISLGREKVTNIILKFCDYIKSKCFKVGIYASLYNFNNSFIDSKLENYERWIAQWSTNFDYHGKCGMWQFGGETNFIRNNVIAGQVVDQDYMLYDYLKDKEPEIIEKENKEKMTIEKAVKKVVDIALGEVGYKEKASNYMLDDKYANAGDANYTKYARDLDSINWFYNGKKQGFAYCDMFNDWVFGKAFGFELARQILYQPYYSAGAGCSFSMDYYRTNGAFSKTPQVGSQIFFGSYGNVGHTGIVVDVIGDKVYTVEGNTSDGVYKIEYNIYDNRILGYGRPNYALVCDVYEEGNKDEEIIYDNKISSIKDVQHFLNKKYIDCFKVRLDEDDEYGSLTKEALVMSVQKEISCEIDGVFGYNDKYKFPILKFGAEGDITKLVQCMLICKKYWIGSDGADGEYGANTKNAINRFQVRESLFVDGECGPETAYKLFN
Other Proteins in cluster: phalp2_34377
Total (incl. this protein): 15 Avg length: 510,3 Avg pI: 7,19
Protein ID Length (AA) pI
4dm6y 539 5,08825
23fgP 536 4,77916
23urx 491 6,62876
3ZV80 507 4,98611
3gav5 491 6,62876
3onB9 670 5,67801
5R48K 475 8,91374
66zBU 475 8,84037
6a0MH 475 8,91909
6rO1i 491 8,13722
6v0Gc 475 8,91896
7nFxr 491 7,52676
88dUg 475 8,76752
8jGu0 573 5,29645
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38736
13rhz
 58 37,3% 453 2.717E-115
2 phalp2_4916
6k3vw
 208 29,2% 553 7.408E-113
3 phalp2_22696
7Vmwp
 2 34,3% 393 5.328E-91
4 phalp2_1134
5riG
 24 31,3% 466 2.218E-72
5 phalp2_38640
41jQJ
 13 33,6% 404 5.569E-72
6 phalp2_34762
3ij83
 364 32,6% 417 5.543E-59
7 phalp2_16417
6gC98
 231 32,5% 418 1.468E-55
8 phalp2_3229
2bNef
 21 23,3% 574 2.817E-49
9 phalp2_7267
3WKbo
 12 26,3% 539 5.133E-49
10 phalp2_2537
6a7No
 192 24,3% 542 4.591E-47

Domains

Domains
GH25
CHAP
PG_1
Representative sequence (used for alignment): 4dm6y (539 AA)
Member sequence: 3mrc2 (490 AA)
1 539 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471, PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4dm6y) rather than this protein.
PDB ID
4dm6y
Method AlphaFoldv2
Resolution 90.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50