Protein

Protein accession
3mezk [EnVhog]
Representative
3uisM
Source
EnVhog (cluster: phalp2_33955)
Protein name
3mezk
Lysin probability
98%
PhaLP type
endolysin
Probability: 94% (predicted by ML model)
Protein sequence
MSKRIETPFTSEHLVAFCEKFLGMPYWYGTCVYKCTESLRSRKAKQYPSHYGSSRTSRYKDDIAKKNVCADCVGMIKGYMWTGGGEGVIEAIGADKTFTSKYGGNGCPDYGANFMFSYAKKKGCAWGTISTLPEVPGVALCASGHIGVYVGNGYAIEERGFNYGCVKTKVSERKWTHWCQLPFIDYGDAPFTTKAETTATEYTLGSRSLTKSMKGTDVKTLQELLLQLGYTLPKYGADGDYGKETIAAVTAFQKKVGIKADGVYGAQTHTALMSAVAENDNGTATVDPEPETPSDTQHTPSEDDAPASTPQRVRIVCENGSVNVRIGNDTKYSRITAVKDGATFPWVATAQNGWQAIEINGQVGWVSGKYSVAE
Physico‐chemical
properties
protein length:374 AA
molecular weight:40635,3 Da
isoelectric point:7,90
hydropathy:-0,41
Representative Protein Details
Accession
3uisM
Protein name
3uisM
Sequence length
373 AA
Molecular weight
40641,18210 Da
Isoelectric point
5,59355
Sequence
MDMEARKLVPLTNEHFAAFLENMLGAPYWYGTCMYKCTEALRARKARQYPSHYSEKRTAQYKRDIEEKKVCADCIGAAKGYAWTDGGQGVIEAIGTDAAIANRYGSNKCPDKGANGMFAYAKSKGMAWGTIDTIPEIVGLAVTTAGHVGYYIGGGYVIEFKGFAYGSVKTELKKGKWTHWYMLPFLDYGTADVTPSEQPDAGENQDATYTLGSRLLKKGSQGEDVRELQRILLELGYALGSYGEGGDGVDGKFGAATEKAVRAFQRNQQIAVDGKYGSVTHAALMGALADQDAMNTDDAQDENETPEGKTLRITADGVNVRTGPDKAFKIITRVNRGERFEYVATAEKQGWYAALIGGKVGWVCGEYAEVEEA
Other Proteins in cluster: phalp2_33955
Total (incl. this protein): 135 Avg length: 347,3 Avg pI: 7,73
Protein ID Length (AA) pI
3uisM 373 5,59355
10E61 362 7,96012
13ELM 367 8,29980
14Wus 352 8,54111
15JS4 374 8,09628
1G1bU 307 4,71686
1GLw3 364 5,49044
1Nygy 328 5,51875
1gA9g 351 7,10575
1gCbd 284 9,17877
1gD45 355 9,23711
1gGxn 347 6,42783
1kdFN 361 5,30179
1m5k7 364 5,64811
1nXn2 373 7,11746
1no8J 381 8,94236
1no9L 359 5,34942
1qC2H 280 8,90400
21mSf 334 8,79144
23yeL 302 5,25212
24sho 301 5,19244
2L7PK 291 8,13219
2Pb7g 373 8,29768
2WEp8 400 7,92234
2WF1c 361 8,87744
2WF4k 367 8,34010
2fZgS 290 8,63349
2lGcm 368 6,46330
2mcCk 365 8,85907
2o2EH 372 5,81420
2oi41 290 8,62253
2ojOU 342 6,22423
2osaz 500 6,24151
30Gs 265 8,39838
38Ien 328 9,60336
3LQ32 279 9,26722
3PLC6 367 5,86586
3PMiU 368 8,23998
3PVyG 390 5,86950
3Pxx6 337 5,73826
3Q0HB 365 6,20394
3Q3eI 362 8,32862
3TM2v 307 5,17118
3ZsZL 359 8,79067
3ZtJ2 380 8,79608
3ZtoP 269 8,73471
3a68M 369 7,51965
3aoYk 365 8,28691
3fM56 259 9,12661
3h4Us 262 9,31151
3ifmN 367 8,05611
3mfmZ 358 8,64310
3nG9R 364 5,38916
3nHNv 378 6,37304
3nHPh 359 7,58922
3nISA 360 8,43467
3nMFt 358 5,46737
3nN2i 368 7,97675
3nNMm 369 6,54702
3o33U 363 7,00941
3o8LU 364 9,18715
3sntJ 365 5,89423
3tRXU 372 7,57854
3tSTI 363 7,95110
3tvZM 376 8,54653
3tvck 382 7,54432
3tw9k 362 8,79615
3u87A 356 8,75083
3uBNY 376 8,57135
3uC12 358 8,63227
3uhWV 365 8,77146
3ulsm 367 8,52673
3us0q 357 8,37407
3usco 366 8,43138
3v4Xu 358 8,52216
3vFis 269 9,20862
3vGCF 365 8,77146
3vVky 362 5,23421
3vdTx 366 7,90803
3voDz 363 5,71695
3vxfU 366 7,97656
3vyYv 368 8,68642
3wLbn 368 8,90671
3wbkc 372 5,48214
3whWS 359 8,44718
3xwGF 360 5,77958
3y7ln 364 5,28184
3y7v3 373 5,54728
3y9KU 357 8,64104
3yi0m 358 8,92554
40dBq 340 6,25856
45f2U 368 7,51516
45s0T 348 9,38223
4Gn13 279 9,13712
4MjPU 262 9,03694
4OdFx 305 8,58546
4UFZN 367 8,05921
4UhQn 373 5,26439
4VUNG 365 8,90677
4kblD 363 9,36663
4kbmY 263 9,12468
5ABE 355 8,86771
5LMHC 373 6,67394
5Lhf7 373 5,72939
5P62T 378 8,78764
5XEGu 363 6,71203
613uw 373 5,72951
61exQ 361 8,59430
66PT 363 7,95110
66uL5 372 8,44292
6Pn4C 284 9,37482
6R8px 290 9,38152
6UM7d 367 8,05205
6agpr 358 9,13925
6cx1p 268 9,33852
6hU3s 367 8,79028
6nPcg 364 7,58939
6oOm 284 9,39209
6vhP3 364 8,70215
71jO0 384 6,40322
71jVA 267 8,92541
7DH85 290 9,25619
7Uo0l 258 8,64774
7WSpk 363 5,22171
7nFzL 279 8,80021
7nFzh 283 8,57747
7q154 367 8,06224
84Sr7 374 7,52573
8bAGk 358 8,62711
8mptk 275 7,58490
R9wm 368 7,56222
pRKS 358 8,88898
yive 365 7,08546
z9xS 369 8,41669
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34532
4UelR
 2 39,8% 369 6.854E-116
2 phalp2_31501
3TJjZ
 324 38,9% 277 1.505E-82
3 phalp2_23391
5URxG
 99 37,3% 241 2.177E-57
4 phalp2_32958
3ZDZv
 229 33,8% 272 5.434E-48
5 phalp2_20477
3TDR4
 13 31,5% 295 4.046E-46
6 phalp2_34071
8r4Zl
 11 36,7% 245 1.018E-45
7 phalp2_29727
1mb2p
 5 29,7% 249 1.177E-40
8 phalp2_9688
23BCv
 75 31,9% 282 1.512E-36
9 phalp2_18241
4Udjz
 1 24,0% 353 2.050E-36
10 phalp2_21023
7YTt
 3 27,9% 301 1.955E-34

Domains

Domains
Unannotated
PG_1
SH3_3
Representative sequence (used for alignment): 3uisM (373 AA)
Member sequence: 3mezk (374 AA)
1 373 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3uisM) rather than this protein.
PDB ID
3uisM
Method AlphaFoldv2
Resolution 85.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50