Protein

Protein accession
2tfo4 [EnVhog]
Representative
7cT88
Source
EnVhog (cluster: phalp2_7772)
Protein name
2tfo4
Lysin probability
99%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSNFKILTTDELITYTKNFKWTRKFSEYQIHHTWKPEHKDFNGSNGIALQEGMRNYHMNNLGWQAIGQHLSLLPDGKWVTGRDFNIIPASVSGRNSLCFLAIEMIGNFDIGHDKLEGEQLNSIIKFVNWGINYYNLGTKGIVFHREYNPKTCPGTSIDKKWFVDKVVNYKEKQENNNNNNKKDEINNDMAILNTKNKANVKVNNKDVFVENYNIDGHIYMQVKDLANMFGKTVEWDDKTKTISIK
Physico‐chemical
properties
protein length:245 AA
molecular weight:28460,9 Da
isoelectric point:8,82
hydropathy:-0,70
Representative Protein Details
Accession
7cT88
Protein name
7cT88
Sequence length
174 AA
Molecular weight
19019,21410 Da
Isoelectric point
4,90744
Sequence
MSQGWSDIAQHATIDPDGYIWSGRDLLTPPASATGFNDPDSDGVHPFMFEMIGNFDAGKEKLEGAQLATATGLCFAIMQLWRRGSDMVKFHREFTTLKTCPGSGIDKNEFVAEVEKHGIKVSAPSSVRVVVNGNPVTDFIEKDGRIYVQLKALEDALGGDLRWDVDTKTASLNI
Other Proteins in cluster: phalp2_7772
Total (incl. this protein): 17 Avg length: 226,5 Avg pI: 7,98
Protein ID Length (AA) pI
7cT88 174 4,90744
14u0d 268 8,43951
16lqG 233 8,49070
2H9aR 268 7,82500
2XvHV 172 6,30512
2b9eZ 215 7,09881
3OPRk 215 9,28211
3cx8U 221 7,86574
3nim5 221 8,67056
3zZJL 217 6,82610
4OEtH 260 8,93417
6UHDU 237 8,93637
7FbzP 213 9,45005
7GhbF 239 9,18354
7rSW5 235 7,33458
csq7 218 7,26950
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1833
3nHDC
 39 25,4% 157 4.988E-22
2 phalp2_13177
2nG2h
 13 33,5% 164 8.450E-16
3 phalp2_39314
4m1un
 3 24,5% 163 4.162E-13
4 phalp2_12934
2XGYf
 62 30,5% 167 7.723E-13
5 phalp2_7609
5IQgF
 2 20,8% 211 9.190E-10
6 phalp2_26914
4sxVx
 24 29,4% 119 2.304E-09
7 phalp2_17106
2tHnh
 282 30,4% 115 3.129E-09
8 phalp2_5712
4IjX3
 263 27,7% 119 4.249E-09
9 phalp2_22314
agEM
 1 23,7% 156 8.986E-08
10 phalp2_26870
4cmU8
 1 26,8% 138 1.651E-07

Domains

Domains
Unannotated
Unannotated
Representative sequence (used for alignment): 7cT88 (174 AA)
Member sequence: 2tfo4 (245 AA)
1 174 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
2tfo4
Method AlphaFoldv2
Resolution 87.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7cT88) rather than this protein.
PDB ID
7cT88
Method AlphaFoldv2
Resolution 89.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50