Protein

Protein accession
2fXg5 [EnVhog]
Representative
45lpM
Source
EnVhog (cluster: phalp2_36672)
Protein name
2fXg5
Lysin probability
99%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNNTGAGLGGLLLKIVQYFQTKNPCYKAGKRITPSGIVVHSTGANNPYIRRYVGPDDGTLGPNKYGNHWNKSTATKCVHAFIGKVDDGSLAVYQTLPWDYRCWGVAKGKNGSYNDSHIQFEICEDGLNDEAYYKEAFSLAARLCAYLCQEYGIKPENVVGHYEAHAAGYGSNHGDPKNWQRKFGGSMDAFRAEVAALMGAENIPADVTTGQEEKEPHAKAPESAKEASKAQGGVNMPTIRNGAHGTAVKVLQRLLIVNGAKLSKYGADGKCGAETVAAVKAFQTAHNLTPDGICGPLTWAALAG
Physico‐chemical
properties
protein length:304 AA
molecular weight:32510,2 Da
isoelectric point:8,50
hydropathy:-0,42
Representative Protein Details
Accession
45lpM
Protein name
45lpM
Sequence length
297 AA
Molecular weight
32760,61910 Da
Isoelectric point
9,31937
Sequence
MEIIRYYQTKNPCYISGRKIKPSGIVVHSTGANNPYLKRYVGPDDGVLGQNQYNNHWNQASANKCVHAWIGKAADGSVKVYQTLPWDYRCWGVGSGKKGSYNATHIQFEICEDSKKDQAYYQEAFTLAQQLCEFLCNEYGIKNENIVGHYEAWAAGYGSNHADPKPWQKKHKGSMAQFRAVVNTLQNGGKSPSQVDLKQAEQLASNTKETAEKPTTKPTQTIQAGTGVITMNTLRKGDKGTQVKVLQWLLSLNGYNVGTVDGIFGEKTLKAVKAYQTAKGLSADGIVGKNTWAKLLA
Other Proteins in cluster: phalp2_36672
Total (incl. this protein): 229 Avg length: 290,9 Avg pI: 7,41
Protein ID Length (AA) pI
45lpM 297 9,31937
13A2N 330 9,39841
16RSD 228 8,60616
1AQQE 232 9,22280
1EnuV 229 9,06395
1G8tu 288 9,02449
1GI2P 302 8,62653
1Gd3j 320 4,99844
1bOnM 301 9,33007
1bOxw 232 9,04325
1gAd8 283 9,13815
1gEdf 293 9,24749
1gFbv 290 8,72104
1gFc8 298 8,62195
1gGLZ 286 8,59926
1gJWj 295 7,31674
1gxyf 297 7,27269
1gzP9 287 8,59752
1k2lN 229 8,93611
1l9my 314 8,00196
1lzf9 324 8,32978
1n14P 258 7,14451
1pzEu 229 8,92721
1r6Qj 232 9,22312
21re7 330 6,32637
23IJs 329 5,60918
23Maf 333 4,96883
2UmqK 356 9,16516
2Xvlq 304 8,91999
2aX6c 326 9,09702
2aXk0 232 9,14905
2bO6r 328 4,90352
2bXva 293 8,74174
2c6Jl 272 8,42552
2di4U 265 6,78558
2fWbF 294 9,10572
2fX06 315 8,84089
2ltjp 265 6,58880
2o99J 297 9,07265
2zLw2 279 5,91560
35NP0 335 7,69426
38GeI 309 8,06636
3B2kN 258 6,82008
3B3jO 265 7,17100
3Gtp6 347 5,68352
3LPag 300 8,67108
3PAGH 300 6,45778
3PBSj 293 9,32047
3PBpU 290 8,90890
3PDLM 257 9,33162
3PNw3 330 4,94757
3PTgL 328 5,42968
3PYHK 293 9,00490
3PYOC 302 8,70828
3PziF 295 7,76093
3Q1Lu 293 9,10598
3TL2r 358 4,77683
3TS6m 333 4,99628
3VKpj 343 5,12912
3WEA8 343 5,13821
3Xf36 233 9,24639
3ddpX 235 9,34690
3g9Hl 313 5,59849
3gU5B 261 6,65917
3lBEk 229 9,13822
3nzTP 305 9,38378
3o7Em 297 8,33333
3o8IE 296 9,26006
3rOas 229 9,48164
3tA6A 265 6,44977
3tTES 265 6,44977
3upwa 345 6,40311
3uyJP 265 6,62728
3vIKT 265 7,17128
3vvRU 265 6,62779
3wjUP 347 5,76293
3yLyD 265 5,91486
41ebu 337 5,53301
453yS 232 9,16026
45yHS 282 8,94152
4GO4x 232 8,95474
4Lc7q 323 5,48629
4LoG5 296 9,37675
4NMpc 233 8,78609
4NQub 326 8,79138
4TxRy 315 8,82670
4UFO8 256 6,65627
4USr7 275 9,49698
4Vz1R 344 9,23485
4j4Yk 239 8,53041
4j5ng 324 8,88460
4j89M 232 9,31273
4tIRo 321 9,21719
4tKD5 330 9,35083
4tMRE 229 9,23466
4uSuV 331 8,94436
4udgg 238 9,37133
4ufDl 229 9,16014
4xSew 326 9,06079
5JZm1 258 6,29864
5L8so 265 7,12019
5L8uA 347 6,49251
5O2Fo 258 6,44915
5Psmw 258 6,16660
5Qaaj 301 6,00961
5QejU 258 6,19297
5RQau 265 6,58874
5Rpdm 265 7,62742
5SAh8 261 6,62682
5SAha 258 6,16660
5SKeB 265 6,78467
5T50m 265 6,44977
5UxDm 265 6,44977
5Vubf 264 6,58795
5X3Nq 264 6,82047
5Y4pX 265 6,85338
5Yuuj 265 6,44915
6070T 347 5,81806
60Jop 347 5,78902
624It 347 5,76628
629IA 265 6,44977
63IyO 347 5,93930
649Gp 265 7,61452
64lD9 261 6,40589
64leC 347 5,78492
657jO 347 6,49251
6591B 424 6,12323
65CZc 261 6,44915
65Km4 347 5,64794
65WFR 265 7,62776
65a88 258 6,25123
67AtX 265 6,82025
68Fcu 265 6,85589
68PkB 265 6,78415
68XR2 299 6,15444
6936l 347 5,59150
69tpJ 258 6,44909
6UIqW 315 6,75750
6UJ2N 324 5,62862
6aCKj 347 6,36554
6b5Ej 347 5,94925
6c3o0 347 5,65101
6dOnt 265 7,62753
6dPfw 345 5,44145
6f6pB 258 7,11916
6ghh1 265 6,30017
6gnPo 347 5,65101
6i4bo 350 5,76526
6jDxG 265 6,82070
6kqa6 265 6,40708
6lVSN 341 9,66931
6lZvT 266 6,82070
6leFy 265 6,44977
6mHic 347 5,76293
6nbwb 347 6,09708
6njYA 347 5,76316
6o471 265 7,14684
6o7c2 265 6,82070
6o7dD 265 7,17100
6oTK3 265 7,60644
6odQ 233 9,17122
6oqy6 265 7,62742
6p2Wo 347 5,76736
6p7Ui 261 6,44915
6p7V7 265 7,60445
6pE5O 347 5,94925
6pZkp 347 7,15861
6qiDB 265 6,85316
6qkmc 265 6,82093
6qupI 330 9,68968
6rDHe 258 6,62728
6sJZk 345 5,56763
6tNze 347 5,76316
6uLZh 347 5,76736
6vohy 265 6,62813
6whWU 265 6,44932
72xKN 257 9,15375
72xiP 229 8,66515
7BJGl 335 9,52748
7BJGp 333 9,57177
7BdvG 229 9,23466
7NN45 347 5,77941
7VQ3t 265 6,85316
7XvYQ 330 9,75872
7Y89z 347 5,80732
7YTW 341 9,57273
7Yxo9 265 6,62699
7ZIX3 301 5,87803
7cHMc 351 9,60381
7pcSN 344 9,24162
7qYqP 346 9,27347
7sbdI 235 9,26322
7w8XU 326 8,90491
7wMyq 229 9,28823
7zb0t 229 9,32575
81lcq 258 6,44915
81vx 319 5,61088
834cH 391 6,36201
83w32 265 6,85338
84pix 258 6,40441
85gBq 258 7,11842
85ikH 301 5,63652
85vX2 301 5,88081
88pLs 351 9,08858
8brQN 255 6,79194
8cE9o 258 6,85236
8cxkZ 265 6,85338
8dhDw 311 6,88516
8eMw5 330 9,60039
8faYz 265 6,85293
8frp6 258 6,54492
8hO2R 265 6,54486
8jD2P 265 6,62734
8jvIO 377 9,29958
8kQ20 265 6,85338
8m4sZ 258 5,91037
8mL7L 258 6,58732
8miDd 240 8,90046
8moGB 357 4,93348
8om9B 299 5,87035
8owew 265 6,78393
8qnov 290 9,87316
8rISm 301 5,75383
D5hl 232 9,31293
ZzIl 285 6,15722
aPfJ 245 8,75946
ePH9 229 8,92721
qmlz 265 6,62734
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35488
tqvH
 739 53,8% 195 8.348E-100
2 phalp2_8073
62PL1
 35 44,0% 209 1.602E-78
3 phalp2_33823
1lgPb
 23 35,1% 299 2.159E-72
4 phalp2_25741
4Lci3
 6 40,3% 203 2.614E-68
5 phalp2_32070
5P7Lm
 156 34,4% 209 1.420E-57
6 phalp2_17257
3WAN9
 1 39,5% 187 8.240E-56
7 phalp2_24341
3TP9g
 1 33,1% 223 3.135E-43
8 phalp2_2331
4MNkD
 32 24,2% 326 3.659E-35
9 phalp2_17898
EGF4
 130 28,0% 310 4.368E-32
10 phalp2_902
8sXPL
 11 20,7% 294 8.853E-25

Domains

Domains
Ami2
PG_1
Representative sequence (used for alignment): 45lpM (297 AA)
Member sequence: 2fXg5 (304 AA)
1 297 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (45lpM) rather than this protein.
PDB ID
45lpM
Method AlphaFoldv2
Resolution 87.08
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50