Protein

Protein accession
21R27 [EnVhog]
Representative
3h23S
Source
EnVhog (cluster: phalp2_9994)
Protein name
21R27
Lysin probability
97%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MGSVYIDVSQYNGKITWNRVDADGVFIRAAYRGYSAGVIKEDARFQENIEGAEKAGIPIGLYFMSQAISESEAYAEAAYCLEICKKYKVTLPVVFDCEYSGDKNYNGRADHLSKQQRTAIINKFCETIAKGGQIPGVYSSTSWYTSNLIPANLMNKNYFIWCAQYNTSCKLTVLDWHLWQYTSKGSMNGISGNVDMSKTRDGRKLPDVLAESIGRASSGASIGNENKSEVKIYVTDEVMSLKKAETKNARFYIGDKPTNFKPYEFACHNGADAIKVDGRLIKVLQKIREHFGKPVSITSGYRTPEYNTKVGGAKNSYHVKGMAADITVTGVANREVAKFAATITNGVGFYNYTGGFVHVDVRGSKYFWQQDAKNAKYYTVAGFNEDPAIRPTLRYNDRGAYVKELQGLLGIGTDGTFKSKTEEAVRKFQKKHGLVKDGVVGPKTWECLLK
Physico‐chemical
properties
protein length:450 AA
molecular weight:50013,1 Da
isoelectric point:9,18
hydropathy:-0,44
Representative Protein Details
Accession
3h23S
Protein name
3h23S
Sequence length
429 AA
Molecular weight
48862,77900 Da
Isoelectric point
7,54881
Sequence
MNGIDISESQKYINLSLIKCDFVIVKATEGKTYTDPCFFQHINNAKKLGKLLGFYHFARPENNRPEEEVQNFLNVIGSYLGEGIPFLDWESSGKYDTAWAKQWLDIFYQRTGIKPIIYMSVLSCEHAYNWSNVAPYYKLWIAKYRDNGIDYNYDMSNAGKSPVPKYWDTYVMWQWTSVGRLDGYGGDLDCDLFYGTDVEWKKLCKKEGEKPMPEYKYFEVLSGVNKYSKKEHGDMFFTIDGRVSNFQIREFACKDGSDEILIDGDLVRRLQDCRDKFGVTTINSAYRTPAWNAKVGGATNSQHVKGKASDTVCKNTSPLEVAMYAEAMGMGGIGLYSSFTHIDTRDGKARWDSRSGREVGVATFLKTIKLGSRGEEVKIAQRYLGISKDGIDGIFGTNTRKATLEFQHLHHLTEDGIIGIQTWTKLLTR
Other Proteins in cluster: phalp2_9994
Total (incl. this protein): 34 Avg length: 421,3 Avg pI: 7,69
Protein ID Length (AA) pI
3h23S 429 7,54881
1HsLJ 450 9,05028
1oeDu 435 8,03761
21mwe 545 8,45266
21r2v 318 5,59741
23CSs 503 8,44138
23eNZ 503 6,61017
23uMc 503 6,86504
24lZI 503 6,43033
3TF9w 427 5,89047
3TFuA 453 8,83160
3VL0d 423 6,21008
3VLxV 503 6,83571
3WOSR 545 6,19155
3ZxlF 443 6,56527
3fJYn 427 6,42829
3o2qU 443 7,98771
3yktX 441 8,13315
41a8p 327 5,82585
41lmR 443 7,57581
41nRx 422 6,41430
4L45C 341 8,62492
4LdAX 420 7,57564
4xD17 337 9,04358
5KWEI 367 9,03752
5RxVP 364 9,27141
5UwxH 364 9,21306
6dcPJ 364 9,21313
6jyNU 364 9,21313
6uwLF 355 8,85359
71jhn 427 6,48206
a5BC 423 7,06636
ndnN 261 8,91638
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35708
3PWv2
 29 32,8% 377 8.837E-80
2 phalp2_39458
4VDTp
 155 25,5% 430 4.817E-42
3 phalp2_2537
6a7No
 192 21,5% 441 1.347E-31
4 phalp2_16855
1Jgdv
 1 20,8% 451 6.843E-29
5 phalp2_4916
6k3vw
 208 23,2% 504 1.077E-25
6 phalp2_3439
3WDPn
 5 17,8% 438 2.155E-21
7 phalp2_12693
24JaA
 16 19,9% 437 5.039E-17

Domains

Domains
GH25
PET_M15
PG_1
Representative sequence (used for alignment): 3h23S (429 AA)
Member sequence: 21R27 (450 AA)
1 429 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471, PF08291

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3h23S) rather than this protein.
PDB ID
3h23S
Method AlphaFoldv2
Resolution 94.31
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50