protein_ID ▲▼ | source ▲▼ | pmid ▲▼ | title ▲▼ | authors ▲▼ | date_of_publication ▲▼ |
---|---|---|---|---|---|
2136 | doi | 10.1016/j.cell.2019.01.003 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target | Zhang Bing; Li Jun; Yang Xiaolin; Wu Lijie; Zhang Jia; Yang Yang; Zhao Yao; Zhang Lu; Yang Xiuna; Yang Xiaobao; Cheng Xi; Liu Zhijie; Jiang Biao; Jiang Hualiang; Guddat Luke W.; Yang Haitao; Rao Zihe | 2019-01-01 |
2136 | doi | 10.1016/j.chembiol.2021.04.024 | Targeting allostery in the Dynein motor domain with small molecule inhibitors | Santarossa Cristina C.; Mickolajczyk Keith J.; Steinman Jonathan B.; Urnavicius Linas; Chen Nan; Hirata Yasuhiro; Fukase Yoshiyuki; Coudray Nicolas; Ekiert Damian C.; Bhabha Gira; Kapoor Tarun M. | 2021-10-01 |
2136 | doi | 10.1016/j.str.2014.08.022 | Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis | Thorsen Thor Seneca; Matt Rachel; Weis William I.; Kobilka Brian K. | 2014-11-01 |
2136 | doi | 10.1021/acs.jmedchem.9b00410 | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation | Kim Ho Shin; Hammill Jared T.; Scott Daniel C.; Chen Yizhe; Min Jaeki; Rector Jonah; Singh Bhuvanesh; Schulman Brenda A.; Guy R. Kiplin | 2019-09-26 |
2136 | doi | 10.1021/jacs.0c06820 | Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents | Liu Jun; Cheng Rujin; Van Eps Ned; Wang Nanxi; Morizumi Takefumi; Ou Wei-Lin; Klauser Paul C.; Rozovsky Sharon; Ernst Oliver P.; Wang Lei | 2020-10-07 |
2136 | doi | 10.1021/jacs.3c09184 | Cucurbit[7]uril Enhances Distance Measurements of Spin-Labeled Proteins | Yang Zhimin; Stein Richard A.; Pink Maren; Madzelan Peter; Ngendahimana Thacien; Rajca Suchada; Wilson Mark A.; Eaton Sandra S.; Eaton Gareth R.; Mchaourab Hassane S.; Rajca Andrzej | 2023-11-29 |
2136 | doi | 10.1021/jo501625f | X-ray Crystal Structure of Teicoplanin A<sub>2</sub>-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy | Han Sunkyu; Le Binh V.; Hajare Holly S.; Baxter Richard H. G.; Miller Scott J. | 2014-09-19 |
2136 | doi | 10.1038/s41422-020-00424-2 | Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR | Xu Xinyu; Kaindl Jonas; Clark Mary J.; Hübner Harald; Hirata Kunio; Sunahara Roger K.; Gmeiner Peter; Kobilka Brian K.; Liu Xiangyu | 2021-05-01 |
2136 | doi | 10.1038/s41422-021-00566-x | Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition | Yuan Yuan; Jia Guowen; Wu Chao; Wang Wei; Cheng Lin; Li Qian; Li Ziyan; Luo Kaidong; Yang Shengyong; Yan Wei; Su Zhaoming; Shao Zhenhua | 2021-12-01 |
2136 | doi | 10.1038/s41467-020-14884-y | Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands | Fan Luyu; Tan Liang; Chen Zhangcheng; Qi Jianzhong; Nie Fen; Luo Zhipu; Cheng Jianjun; Wang Sheng | 2020-02-26 |
2136 | doi | 10.1038/s41467-021-22924-4 | Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity | Zhou Haibin; Lu Jianfeng; Chinnaswamy Krishnapriya; Stuckey Jeanne A.; Liu Liu; McEachern Donna; Yang Chao-Yie; Bernard Denzil; Shen Hong; Rui Liangyou; Sun Yi; Wang Shaomeng | 2021-05-11 |
2136 | doi | 10.1038/s41467-021-23519-9 | Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist | Sun Bingfa; Feng Dan; Chu Matthew Ling-Hon; Fish Inbar; Lovera Silvia; Sands Zara A.; Kelm Sebastian; Valade Anne; Wood Martyn; Ceska Tom; Kobilka Tong Sun; Lebon Florence; Kobilka Brian K. | 2021-06-03 |
2136 | doi | 10.1038/s41467-021-27391-5 | Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure | Zhou Jia; Hu Qinli; Xiao Xinlong; Yao Deqiang; Ge Shenghong; Ye Jin; Li Haojie; Cai Rujie; Liu Renyang; Meng Fangang; Wang Chao; Zhu Jian-Kang; Lei Mingguang; Xing Weiman | 2021-12-02 |
2136 | doi | 10.1038/s41467-023-39310-x | Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody | Toyoda Yosuke; Zhu Angqi; Kong Fang; Shan Sisi; Zhao Jiawei; Wang Nan; Sun Xiaoou; Zhang Linqi; Yan Chuangye; Kobilka Brian K.; Liu Xiangyu | 2023-06-20 |
2136 | doi | 10.1038/s41586-020-2379-5 | Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane | Yin Jie; Chen Kuang-Yui M.; Clark Mary J.; Hijazi Mahdi; Kumari Punita; Bai Xiao-chen; Sunahara Roger K.; Barth Patrick; Rosenbaum Daniel M. | 2020-08-06 |
2136 | doi | 10.1038/s41586-021-03743-5 | cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila | Slavik Kailey M.; Morehouse Benjamin R.; Ragucci Adelyn E.; Zhou Wen; Ai Xianlong; Chen Yuqiang; Li Lihua; Wei Ziming; Bähre Heike; König Martin; Seifert Roland; Lee Amy S. Y.; Cai Hua; Imler Jean-Luc; Kranzusch Philip J. | 2021-09-02 |
2136 | doi | 10.1038/s41589-020-0549-2 | An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor | Liu Xiangyu; Kaindl Jonas; Korczynska Magdalena; Stößel Anne; Dengler Daniela; Stanek Markus; Hübner Harald; Clark Mary J.; Mahoney Jake; Matt Rachel Ann; Xu Xinyu; Hirata Kunio; Shoichet Brian K.; Sunahara Roger K.; Kobilka Brian K.; Gmeiner Peter | 2020-07-01 |
2136 | doi | 10.1038/s41594-022-00804-9 | Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism | Chang Yong-Gang; Lupton Christopher J.; Bayly-Jones Charles; Keen Alastair C.; D’Andrea Laura; Lucato Christina M.; Steele Joel R.; Venugopal Hari; Schittenhelm Ralf B.; Whisstock James C.; Halls Michelle L.; Ellisdon Andrew M. | 2022-08-01 |
2136 | doi | 10.1039/c7cp03144k | Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals | Consentius Philipp; Gohlke Ulrich; Loll Bernhard; Alings Claudia; Heinemann Udo; Wahl Markus C.; Risse Thomas | 2017-01-01 |
2136 | doi | 10.1073/PNAS.1506242112 | Structural basis of human γ-secretase assembly | Sun Linfeng; Zhao Lingyun; Yang Guanghui; Yan Chuangye; Zhou Rui; Zhou Xiaoyuan; Xie Tian; Zhao Yanyu; Wu Shenjie; Li Xueming; Shi Yigong | 2015-05-12 |
2136 | doi | 10.1073/pnas.1914446116 | Crystal structure of the M <sub>5</sub> muscarinic acetylcholine receptor | Vuckovic Ziva; Gentry Patrick R.; Berizzi Alice E.; Hirata Kunio; Varghese Swapna; Thompson Geoff; van der Westhuizen Emma T.; Burger Wessel A. C.; Rahmani Raphaël; Valant Celine; Langmead Christopher J.; Lindsley Craig W.; Baell Jonathan B.; Tobin Andrew B.; Sexton Patrick M.; Christopoulos Arthur; Thal David M. | 2019-12-17 |
2136 | doi | 10.1073/pnas.2102813118 | Molecular basis for lipid recognition by the prostaglandin D<sub>2</sub>receptor CRTH2 | Liu Heng; Deepak R. N. V. Krishna; Shiriaeva Anna; Gati Cornelius; Batyuk Alexander; Hu Hao; Weierstall Uwe; Liu Wei; Wang Lei; Cherezov Vadim; Fan Hao; Zhang Cheng | 2021-08-10 |
2136 | doi | 10.1073/pnas.2106195118 | Energy penalties enhance flexible receptor docking in a model cavity | Kamenik Anna S.; Singh Isha; Lak Parnian; Balius Trent E.; Liedl Klaus R.; Shoichet Brian K. | 2021-09-07 |
2136 | doi | 10.1107/S1399004715009505 | The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design | Klima Martin; Baumlova Adriana; Chalupska Dominika; Hřebabecký Hubert; Dejmek Milan; Nencka Radim; Boura Evzen | 2015-07-01 |
2136 | doi | 10.1107/S2052252519013137 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers | Ishchenko Andrii; Stauch Benjamin; Han Gye Won; Batyuk Alexander; Shiriaeva Anna; Li Chufeng; Zatsepin Nadia; Weierstall Uwe; Liu Wei; Nango Eriko; Nakane Takanori; Tanaka Rie; Tono Kensuke; Joti Yasumasa; Iwata So; Moraes Isabel; Gati Cornelius; Cherezov Vadim | 2019-11-01 |
Showing 676–700 of 10708 total items.